Why have ovarian cancer mortality rates declined? Part III. Prospects for the future

Why have ovarian cancer mortality rates declined? Part I. Incidence

“…Few risk factors that increase the risk of ovarian cancer have been confirmed; these include hormone replacement therapy [38], talcum powder [39], high body mass index [40] and endometriosis [41] and are not considered here. The role of genetic predisposition in ovarian cancer is discussed in part III [9].…”

“…In part III, we discuss future prospects for reducing ovarian cancer mortality, which incorporate genetic testing, preventive surgery, screening and treatment [9]. …”

“…In part II, we consider if the decline in mortality was due to new and better treatments [8]. In part III, we discuss potential approaches for reducing ovarian cancer mortality in the future, through prevention, early detection and treatment [9].…”

Why have ovarian cancer mortality rates declined? Part II. Case-fatality

“…The decline in mortality is the consequence of a decline in ovarian cancer incidence, which was largely due to the introduction of oral contraceptives in 1960 and the expansion in their use until 1990 [1]. In Part III, we discuss potential approaches to standardize the treatment of ovarian cancer using an optimal combination of surgery and chemotherapy in order to improve the cure rate of ovarian cancer [59].…”

Is endometriosis a benign disease? Modern controversial aspects of endometriosis-associated ovarian tumors

“…Это может быть одним из факторов расширения диагностики генетического тестирования для всех женщин в популяции, с последующей билатераль-ной овариэктомией для женщин, при любой опера-ции на брюшной полости [76].…”