Why more keloids on back than on front of earlobe

Slobodkin, David

doi:10.1016/0140-6736(90)90529-e

Cited by 10 publications

(4 citation statements)

References 5 publications

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“…Lobular scarring is the fifth most common reason for adult and pediatric dermatology consultations in a survey of black patients attending a London hospital 6 . It was documented that auricular keloids develop more frequently on the posterior aspect of the lobule than on its anterior surface 7 . A family genetic predisposition to the formation of keloids has been described 8 …”

mentioning

confidence: 99%

Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies

Har‐Shai

Sabo

Rohde

et al. 2006

Wound Repair Regeneration

100

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To explain the mechanism of action of a novel intralesional cryoprobe, thermal behavior measurements, and histological studies were performed in swine muscle specimens after intralesional cryosurgery ex vivo. Slow cooling (20 degrees C/min) and thawing (25 degrees C/min) rates, end temperature of -30 degrees C, produced 8 mm wide diffuse coagulative-type necrosis and a 3 mm-wide transition zone around the cryoprobe. In contrast, contact cryosurgery showed fast cooling and thawing rates (80 degrees C/min) and an end temperature of -100 degrees C. Efficacy and safety of the intralesional cryoprobe was further assessed in ten recalcitrant auricular keloids in nine Caucasian patients. There was a 67.4 +/- 23 percent reduction of scar volume at the end of the 18-month follow-up period after a single intralesional treatment (p < 0.005). Significant reduction of hardness, elevation, and redness as well as itching, pain, and tenderness was documented. The histomorphometric analysis, including spectral and fractal analysis, as well as assessment of the fast Fourier transform algorithm, showed parallel alignment and reorganization of the collagen fibers in the treated scar similar to that in the normal dermis. A long hold time in the deep scar core caused minimal damage to the superficial tissue, including melanocytes. There was no evidence of permanent hypopigmentation, active bleeding, infection, or recurrence. The major advantages of the intralesional cryoprobe, including the marked efficacy of a single treatment, may have a major importance in the clinical application of cryosurgery in the treatment of keloids and of other lesions localized deep in the skin.

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mentioning

confidence: 99%

Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies

Har‐Shai

Sabo

Rohde

et al. 2006

Wound Repair Regeneration

100

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“…This is in agreement with the findings of other studies. 4 Because piercing is a perforating lesion, keloids are expected to develop similarly on both sides of the ear. But, curiously, keloids mostly occur on the posterior surface of the ear, raising the question: Why does it happen?…”

Section: Discussionmentioning

confidence: 99%

Does ear keloid formation depend on the type of earrings or piercing jewellery?

et al. 2015

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The ear is one of the most common sites of keloid formation, usually associated with the wearing of earrings. However, although this is a small perforating lesion that is equal on both sides, keloids are bigger and more prevalent on the posterior surface. In this study, 141 keloids were evaluated, most of which were located on the posterior surface of the earlobe and caused by the piercing of the ear. Most of the earrings and piercing jewellery used had metallic backs. The more frequent occurrence of earlobe keloids on the posterior surface of the ear therefore may be associated with the exacerbation of local neurogenic inflammation caused by the metallic backs.

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“…In our case 1, repiercing was performed on the reconstructed earlobe. Slobodkin et al 15 have described that of the reasons for keloid formation is the deep dermis being brought into contact with more superficial layers by piercing. Therefore, case 1 must continue to be cared for considering the possibility of regrowth of the keloid.…”

Section: Discussionmentioning

confidence: 99%

“…In consideration of these advantages and disadvantages, this technique is one of the useful operative methods for reconstruction after resection of earlobe keloid. Especially for cases of earlobe keloids developing after ear piercing, as the lesion occurs more commonly on the posterior side than on the anterior side, 15 this may be the most suitable technique.…”

Section: Discussionmentioning

confidence: 99%