“…Additionally, significant variation in consumption among different countries and ethnicities, even among different regions within the same country and different age groups within the same population, has been observed. Intriguingly, many of the peculiar changes in IBD, such as the recent decrease in CD but increase in UC in children in Sweden (5), as well as the shared trend of change of pediatric IBD in Sweden with the general population IBD in Denmark but not pediatric IBD in Norway (6), can also be easily explained by the pattern of consumption of some artificial sweeteners and the united hypothesis published earlier (3). Here, I advocate investigating a possible link between dietary chemicals and IBD.…”