Widening of Virchow-Robin spaces in the brain stem causing hemifacial spasm

Solak, Okan; Yaman, Mehmet; Haktanır, Alpay; Ayçiçek, Abdullah; Oruç, Serdar; Kırpıko, Oğuz

doi:10.1016/j.ejrex.2008.10.004

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2018

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“…Dilated Virchow-Robin spaces, which can often be seen in deposition disorders such as mucopolysaccharidosis, have been shown to cause HFS. 7 However, our patient did not have any dilated Virchow-Robin spaces in the brainstem, making this an unlikely etiology in our patient.…”

Section: Discussionmentioning

confidence: 60%

Hemifacial Spasm in Mucopolysaccharidosis Type VI (Maroteaux–Lamy Syndrome)

Karir

Geraghty

Vassilyadi

et al. 2018

Tremor and Other Hyperkinetic Movements

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Background: Hemifacial spasms are involuntary contractions of the muscles of one side of the face.Case Report: Here, we report a 5-year-old female patient with a significant past medical history, including mucopolysaccharidosis type VI, who also presented with hemifacial spasms. Further investigations showed narrowing of skull foramina and hydrocephalus, but no compression of the facial nerve. Carbamazepine was given to the patient, which caused cessation of the spasms.Discussion: Currently, there is no literature discussing the relationship between hemifacial spasms and mucopolysaccharidosis type VI; we have proposed that mucopolysaccharide deposits or dural thickening may contribute to nerve irritation.

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Section: Discussionmentioning

confidence: 60%