Widespread Cytomegalovirus Gastroenterocolitis in a Patient With Acquired Immunodeficiency Syndrome

Knapp, Albert; Horst, Douglas; Eliopoulos, George D.; Gramm, Herbert F.; Gaber, Lillian W.; Falchuk, Kenneth R.; Falchuk, Z. Myron; Trey, Charles

doi:10.1016/s0016-5085(83)80024-9

Cited by 87 publications

(9 citation statements)

References 20 publications

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“…GI involvement with CMV is rare, and most reported cases are in adults following bone-marrow transplantation [12] or associated with acquired immunodeficiency syndrome (AIDS) [9,11]. Only a few pediatric cases have been reported.…”

Section: Discussionmentioning

confidence: 99%

Acute abdominal emergencies associated with cytomegalovirus infection in the young infant

et al. 1988

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Gastrointestinal signs and symptoms have rarely been reported in association with cytomegalovirus (CMV) infection in young infants. However, in 1981 clear pathologic evidence was presented implicating this virus as a cause of hypoganglionosis and bowel dysmotility. We report our experience with four infants with CMV infection in whom gastrointestinal dysfunction was the reason for emergency abdominal operation. Since the association was made retrospectively, we were unable to demonstrate hypoganglionosis, but our experience underscores the need to include CMV intestinal infection in the differential diagnosis of the acute surgical abdomen in young infants.

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Section: Discussionmentioning

confidence: 99%

Acute abdominal emergencies associated with cytomegalovirus infection in the young infant

et al. 1988

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“…Throughout the gastrointestinal tract, infection by cytomegalovirus (CMV) may cause cytopathic effects and the resulting ulceration of the involved mucosa. [12][13][14][15][16] In cytologic specimens, CMV infection is recognized by the presence of a Cowdry type B ("owl's eye") intranuclear inclusion in infected stromal and epithelial ce! :s of the gut.…”

Section: Cytomegalovirusmentioning

confidence: 99%

Alimentary tract cytopathology in human immunodeficiency virus infection: A review of experience in los angeles

Strigle

Gal

Martin

1990

Diagnostic Cytopathology

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In the past decade, over 100,000 cases of the acquired immunodeficiency syndrome (AIDS) have been reported in the United States. Conservative estimates suggest that 1.5 million people are infected with the human immunodeficiency virus (HIV), the etiologic agent of AIDS. Major metropolitan areas, such as Los Angeles, have experienced a rapid increase in the number of AIDS cases. At the Los Angeles County-University of Southern California Medical Center, we have gained significant insight into the cytologic findings associated with HIV infection. Based on our experience, we herein review the technical and morphologic evaluation of alimentary tract cytology specimens from this patient population.

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“…Radiographic and CT findings are not specific, and early lesions may not show up at all Frager et al, 1986). The symptoms and endoscopic, colonoscopic, and radiographic findings in CMV GI disease can mimic those of other ailments, including tumors, inflammatory bowel disease with diffuse mucosal ulceration or granulomatous lesions, and other infectious processes (Elta et al, 1986;Frager et al, 1986;Freedman et al, 1985;Knapp et al, 1983). Diagnosis by biopsy must be made to rule out treatable conditions such as candidiasis.…”

Section: Viruses As Opportunists In Aids Cytomegalovirusmentioning

confidence: 99%

Viral infections in the acquired immunodeficiency syndrome

Miller

Howell

1988

J. Elec. Microsc. Tech.

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The following communication is a tripartite synopsis of the role of viral infection in the acquired immunodeficiency syndrome (AIDS). The first section describes the impact of viral opportunistic infection in AIDS; for each virus, clinical presentation and diagnosis, laboratory diagnostic approaches (with emphasis on electron microscopy), and therapeutic interventions attempted to date are discussed. The second segment explores current theories on the pathogenesis of AIDS, and describes diagnostic and therapeutic approaches to the syndrome itself. The final section catalogues ultrastructural anomalies in the cells of AIDS patients, many of which have been mistakenly identified as etiologic agents.

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Widespread Cytomegalovirus Gastroenterocolitis in a Patient With Acquired Immunodeficiency Syndrome

Cited by 87 publications

References 20 publications

Acute abdominal emergencies associated with cytomegalovirus infection in the young infant

Acute abdominal emergencies associated with cytomegalovirus infection in the young infant

Alimentary tract cytopathology in human immunodeficiency virus infection: A review of experience in los angeles

Viral infections in the acquired immunodeficiency syndrome

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