Widespread occurrence of the antifungal cutaneous bacterium Janthinobacterium lividum on Andean water frogs threatened by fungal disease

Rubio, Andrew O.; Kupferberg, Sarah J.; García, Víctor Vargas; Ttito, Alex; Shepack, Alexander; Catenazzi, Alessandro

doi:10.3354/dao03298

Cited by 6 publications

(7 citation statements)

References 23 publications

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“…A. tumefaciens originates in plants and soil [28,29]. S. maltophilia frequently colonizes humid abiotic surfaces in water installations, mechanical ventilation systems and medical devices [30], as do A. hydrophila [31,32,33] and J. lividum , which are often isolated from water and water-living animals [34]. S. maltophilia is closely related to Pseudomonas and Xanthomonas genera.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Kręgiel

Rygała

Kolesińska

et al. 2019

IJMS

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Antibiofilm strategies may be based on the prevention of initial bacterial adhesion, the inhibition of biofilm maturation or biofilm eradication. N-acetyl-L-cysteine (NAC), widely used in medical treatments, offers an interesting approach to biofilm destruction. However, many Eubacteria strains are able to enzymatically decompose the NAC molecule. This is the first report on the action of two hybrid materials, NAC-Si-1 and NAC-Si-2, against bacteria isolated from a water environment: Agrobacterium tumefaciens, Aeromonas hydrophila, Citrobacter freundii, Enterobacter soli, Janthinobacterium lividum and Stenotrophomonas maltophilia. The NAC was grafted onto functional siloxane polymers to reduce its availability to bacterial enzymes. The results confirm the bioactivity of NAC. However, the final effect of its action was environment- and strain-dependent. Moreover, all the tested bacterial strains showed the ability to degrade NAC by various metabolic routes. The NAC polymers were less effective bacterial inhibitors than NAC, but more effective at eradicating mature bacterial biofilms.

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Section: Resultsmentioning

confidence: 99%

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Kręgiel

Rygała

Kolesińska

et al. 2019

IJMS

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“…(Jiaxian et al 2019), which main sources are soil dust in big cloud droplets (Zhu et al 2018). Janthinobacterium has antifungal properties (Rubio et al 2018) and was found in high mountain lakes and Antarctica (Ahern et al 2007) and alpine cryoconite, and is known for its psychrotolerant properties (Kim et al 2012). It does fit the continental background location of Mount Sonnblick, where low concentrations of aerosol pollution markers (like SO 2 or high PM) would be expected .…”

Section: 8mentioning

confidence: 99%

Microbial composition in seasonal time series of free tropospheric air and precipitation reveals community separation

et al. 2019

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Primary biological aerosols are transported over large distances, are traveling in various media such as dry air masses, clouds or fog, and eventually deposited with dry deposition, especially for larger particles, or precipitation like rain, hail or snow. To investigate relative abundance and diversity of airborne bacterial and fungal communities, samples have been collected with a liquid impinger (Coriolis l) from the top of Mount Sonnblick (3106 m asl, Austrian Alps) from the respective sources under a temporal aspect over four seasons over the year to include all climatic conditions. Bacterial and fungal

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“…For some amphibian species that are resistant to Bd infections or chytridiomycosis, the presence of keystone species that facilitate a more resilient, protective community may contribute to disease resistance [38]. Janthinobacterium lividum produces anti-Bd metabolites, has been used as probiotic against Bd [7,39], and is commonly found in the microbiome of some amphibian taxa [40,41]. For many susceptible amphibians, it is a successful anti-Bd probiotic.…”

Section: Discussionmentioning

confidence: 99%

Recovery and resiliency of skin microbial communities on the southern leopard frog (Lithobates sphenocephalus) following two biotic disturbances

2020

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Background Microorganisms have intimate functional relationships with invertebrate and vertebrate taxa, with the potential to drastically impact health outcomes. Perturbations that affect microbial communities residing on animals can lead to dysbiosis, a change in the functional relationship, often associated with disease. Batrachochytrium dendrobatidis (Bd), a fungal pathogen of amphibians, has been responsible for catastrophic amphibian population declines around the globe. Amphibians harbor a diverse cutaneous microbiome, including some members which are known to be antagonistic to Bd (anti-Bd). Anti-Bd microorganisms facilitate the ability of some frog populations to persist in the presence of Bd, where other populations that lack anti-Bd microorganisms have declined. Research suggests disease-antagonistic properties of the microbiome may be a function of microbial community interactions, rather than individual bacterial species. Conservation efforts have identified amphibian-associated bacteria that exhibit anti-fungal properties for use as ‘probiotics’ on susceptible amphibian populations. Probiotic application, usually with a single bacterial species, may benefit from a greater understanding of amphibian species-specific microbiome responses to disturbances (e.g. dysbiosis vs. recovery). We assessed microbiome responses to two microbial disturbance events over multiple time points. Results Exposing Lithobates sphenocephalus (southern leopard frog) adults to the biopesticidal bacteria Bacillus thuringiensis, followed by exposure to the fungal pathogen Bd, did not have long term impacts on the microbiome. After initial shifts, microbial communities recovered and returned to a state that resembled pre-disturbance. Conclusions Our results indicate microbial communities on L. sphenocephalus are robust and resistant to permanent shifts from some disturbances. This resiliency of microbial communities may explain why L. sphenocephalus is not experiencing the population declines from Bd that impacts many other species. Conservation efforts may benefit from studies outlining amphibian species-specific microbiome responses to disturbances (e.g. dysbiosis vs. recovery). If microbial communities on a threatened amphibian species are unlikely to recover following a disturbance, additional measures may be implemented to ameliorate the impacts of physical and chemical stressors on host-associated microbial communities.

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Widespread occurrence of the antifungal cutaneous bacterium Janthinobacterium lividum on Andean water frogs threatened by fungal disease

Cited by 6 publications

References 23 publications

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Microbial composition in seasonal time series of free tropospheric air and precipitation reveals community separation

Recovery and resiliency of skin microbial communities on the southern leopard frog (Lithobates sphenocephalus) following two biotic disturbances

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