Wild mammals as reservoirs for Rhodesian sleeping sickness in the Serengeti,

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

“…STIB247 is a low virulence T.b. brucei strain that induces a chronic infection and was isolated from a hartebeest in the Serengeti in 1971 ( Geigy et al, 1973 ). TREU927 is the genome reference strain for T. brucei and is more virulent than STIB247.…”

Blood meal analysis of tsetse flies (Glossina pallidipes: Glossinidae) reveals higher host fidelity on wild compared with domestic hosts

“…Wild animals have been reported as reservoir hosts both for AAT (Anderson et al . 2011b; OIE 2013) and HAT (Geigy et al . 1973a; Geigy et al .…”

“…Although there are multiple species of tsetse flies that can transmit multiple species of trypanosomes, Glossina pallidipes is the most economically important species in East Africa 21 , because it is the main vector of Animal African Tryanosomiasis (AAT) and it is also a vector of Human African Trypanosomiasis(HAT). Wild animals have been reported as reservoir hosts both for AAT 3,57 and HAT 25,26,34,73,74 but the extent of transmission across the wildlife-livestock interface remains unclear.…”

Modelling the spatial and temporal distribution of tsetse flies for targeted control

“…In contrast, the Rhodesian form of human trypanosomiasis is zoonotic, and the most effective method is to implement chemoprophylaxis for animals that serve as trypanosome reservoirs (Welburn et al, 2001). Many wild animals act as trypanosome reservoirs, where the pathogen can exist and reproduce naturally without affecting the animal (Geigy et al, 1973;Jordan, 1993;Haydon et al, 2002). Administering mass chemoprophylaxis to wild animals is practically impossible.…”