Wildland-urban interface wildfires have been a significant threat in many countries. This thesis presents an integer two-stage stochastic goal programming model for comprehensive, efficient response to wildfire including firefighting resource allocation and resident evacuation. In contrast to other natural disasters, the progression of wildfires depends on not only the probabilistic fire spread scenarios but also decisions made during firefighting. The proposed model optimizes the resource preparations before the fire starts and resource allocation decisions during the fire event. This model takes into account different wildfire spread scenarios and their impact on high-risk areas. The two objectives considered are minimizing the total cost of operations and property loss and minimizing the number of people at risk to be evacuated. A case study based on Santa Clara County in California, United States of America, is presented to demonstrate the model performance. Quantitative experiments show that this model can help to find efficient solutions by considering a trade-off between two objectives, and varying cell size based on scenarios reduces problem dimension and improves solution time. v ACKNOWLEDGMENTS The completion of this thesis is a result of the support of many people. First, I would like to express my deep and sincere gratitude to Prof. Ayca Erdogan, my thesis advisor. For many times, I felt lost in choosing a suitable direction to continue with my thesis and I realized that challenges came out one after another. Prof. Erdogan always listened to my ideas patiently and figured out key issues. Even if sometimes we touched to an unfamiliar field to both of us, Prof. Erdogan encouraged me to keep reading advanced papers and try to solve problems independently. All her advising and encouragement made me move ahead and keep growing as a beginner in research. Second, I would like to thank Prof. Jacob Tsao, who gave me a lot of useful suggestions about career development and academic direction. In addition, Prof. Tsao made me more confident in myself through his encouragements. Also, I want to thank Prof. Yasser Dessouky, who is an excellent lecturer and taught me systematic thinking in his class. I was encouraged by his lecture to start with this thesis. I also would like to thank Dee King Raub from Santa Clara County Fire Department for providing valuable information of WUI wildfire containment efforts. Lastly, I would like to thank my husband, Yu Ni. When I felt confused about the uncertain future, he always stands by me and encourages me to make efforts toward my career goal. It's impossible to finish this thesis without his continued support. Also, thanks Hongyao Ma and Fenfei Guo for their encouragement on my research work. vi