Willingness and SARS-CoV-2 Vaccination Coverage among Healthcare Workers in China: A Nationwide Study

Abstract

Background: The SARS-CoV-2 vaccine has been widely rolled out globally in the general populations. However, specific data on vaccination confidence, willingness or coverage among health care workers (HCWs) has been less reported. Methods: A cross-sectional online survey was conducted to specify the basic data and patterns of vaccination confidence, willingness and coverage among HCWs nationwide. Results: In total, 2386 out of 2583 (92.4%) participants were enrolled for analysis, and the rates of confidence in vaccine, professional institutes and government were 75.1%, 85.2% and 85.4%, respectively. The overall vaccination coverage rate was 63.6% which was adjusted as 82.8% for participants under current medical conditions or having contraindications. Confidence in vaccine safety was shown to be the most related factor to willingness among doctors, nurses, medical technicians and hospital administrators, while confidence in vaccine effectiveness as well as trust in government played the key role in formulating public health employees’ willingness. 130 (7.1% of 1833) participants reporting willingness still not been vaccinated regardless of contraindications. Multivariate analysis among willingness participants showed that males, aged over 30 years, public health employees and higher vaccination confidence had significantly higher vaccination rates with ORs (95% confidence intervals) as 1.64 (1.08–2.49), 3.14 (2.14–4.62), 2.43 (1.46–4.04) or 2.31 (1.24–4.33). Conclusions: HCWs’ confidence, willingness and coverage rates to the vaccine were generally at high levels. Heterogeneity among HCWs should be considered for future vaccination promotion strategies. The population’s confidence in vaccination is not only the determinant to their willingness, but also guarantees their actual vaccine uptake.

COVID-19 vaccine acceptance among healthcare workers in China: A systematic review and meta-analysis

“…This systematic review and meta-analysis showed a pooled overall acceptance rate (78%) for COVID-19 vaccination among HCWs in China. But this result was lower than the acceptance rate in three previous national cross-sectional studies with more than 2,000 participants (87.94% [32], 80.85% [35], and 84.65% [38], respectively) and slightly higher than the result in a national study [31] with 1,329 participants, which indicated an overall acceptance rate of 76.98%. In addition to the small sample effect, another possible contributor to this finding was that in the latter study, the addition of attitudes of hesitation to the questionnaire led to a lower overall acceptance rate.…”

“…S3 Table represents the quality assessment using the AHRQ appraisal tool and the level of evidence for each included 18 study. In general, two studies were considered high quality [13,34], while the remaining were stated as moderate quality [22][23][24][25][26][27][28][29][30][31][32][33][35][36][37][38]. All included studies were rated "yes" in items 1, 2, and 8, "unclear" in item 4, and "no" in item 9 and 11.…”

“…were conducted across 3 provinces [28,29], and four studies were conducted on whole national scale [31,32,35,38]. Two studies included nurses or practice nurses [24,37], and the remaining studies included different types of HCWs.…”

COVID-19 Vaccine Acceptance and Hesitancy among Health Care Workers (HCWs) In Two Major Urban Centers in Khyber-Pakhtunkhwa, Pakistan

“…The vaccination rates for HCWs were significantly higher in other countries worldwide in the same time frame. 4 Despite many HCWs being vaccinated, vaccine hesitancy among healthcare workers is a contributory factor that needs further study.…”

Seroprevalence in health care workers during the later phase of the second wave: Results of three hospitals in Serbia, prior to vaccine administration

“…An effective vaccine campaign is a necessary tool to reduce rapid SARS-CoV-2 virus transmission [34] . Healthcare professionals have a special and important role in achieving high vaccine coverage in the population [35] , [36] , especially in the new vaccine introduction, such as the mRNA vaccines. Adverse events following the use of mRNK vaccine by healthcare workers have been demonstrated to be benign and similar to those in the general population [37] .…”