Willingness to be vaccinated against COVID-19 is equal in individuals with affective disorders and healthy controls

Fellendorf, Frederike T.; Bonkat, Nina; Platzer, Martina; Schönthaler, Elena; Ratzenhofer, Michaela; Bengesser, Susanne; Dalkner, Nina; Reininghaus, Eva

doi:10.1016/j.jvacx.2022.100186

Cited by 2 publications

(3 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Individuals with AD and HC did not differ in their vaccination status. This has been shown in former Austrian studies with other samples (Fellendorf et al, 2022) as well as in international studies (Batty et al, 2021;Hao et al, 2021;Jefsen et al, 2021), although other studies showed a lower vaccine rate in individuals with psychiatric disorders (Arumuham et al, 2022;Curtis et al, 2022). We suppose a strong influence of socioeconomic circumstances, e.g., age, sex, education, and income, as well as cultural factors, such as governmental regulations in vaccination decision (Schwarzinger et al, 2021;Schernhammer et al, 2022).…”

Section: Discussionmentioning

confidence: 71%

COVID-19 vaccination motivation and underlying believing processes: A comparison study between individuals with affective disorder and healthy controls

et al. 2022

Self Cite

View full text Add to dashboard Cite

BackgroundBelieving processes represent fundamental brain functions between cognition and emotion. Shortly before the introduction of a compulsory vaccination against COVID-19 in Austria, motives and underlying believing processes regarding the vaccination were collected in individuals with affective disorder (AD) and healthy controls (HC).Methods79 individuals with AD and 173 HC were surveyed online to assess believing processes with the parameters of the credition model (narratives, certainty, emotion, mightiness) about (1) the coronavirus itself and (2) why someone is vaccinated or not. In addition, we calculated congruence scores between content of narrative and type of emotion and divided the narrative content into positive, negative, and indifferent.ResultsThere were no differences in vaccination status between AD and HC. Higher levels of certainty were observed in HC compared to AD in both vaccinated and unvaccinated individuals. The effects were higher when asked about the motivation to vaccinate or not than about the coronavirus itself. In HC, more positive emotions and more congruence between emotions and narratives were reported during believing in their vaccination motives. No group differences were found in mightiness for both items. Independently from diagnosis, unvaccinated people had high levels of certainty and more negative emotions and narratives while believing in their motives for not getting vaccinated.ConclusionWhen believing about the COVID-19 vaccination, individuals with AD were more uncertain and experienced fewer positive emotions than HC, although both groups did not differ in vaccination status. These effects were not that strong when believing about the coronavirus in general.

show abstract

Section: Discussionmentioning

confidence: 71%

COVID-19 vaccination motivation and underlying believing processes: A comparison study between individuals with affective disorder and healthy controls

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…Although scarce, there are studies (primarily cross-sectional) reporting conflicting results regarding mental health and actual vaccine uptake. Such studies 7 , 26 found no association between mental health status during rollout and vaccine uptake, while other studies found that better mental health or reduced perceived mental health impact was associated with increased vaccine hesitancy. 8 , 9 One longitudinal study in the general population found that depressive symptom severity prior to rollout was associated with indecisiveness to be vaccinated during rollout.…”

Section: Discussionmentioning

confidence: 97%

“…Existing studies examining mental health and vaccine hesitancy in the general population during the COVID-19 pandemic are mixed, likely due to variations in outcome assessment or inconsistencies in study design. 7–10 Moreover, there are just two quantitative studies examining COVID-19 vaccine hesitancy and attitudes in UK-based HCPs, but neither study included mental health. 11 , 12 As such, mental health as a potential predictor of vaccine attitudes amongst these HCPs has not been investigated.…”

Section: Introductionmentioning

confidence: 99%

Factors influencing attitudes toward vaccine safety and vaccine effectiveness amongst UK healthcare professionals prior to and at the time of COVID-19 vaccine rollout: Insights from the CoPE-HCP cohort study

Collett

Godec

Gupta

2023

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

Given the potential for nosocomial outbreaks, we must understand factors associated with negative vaccine attitudes amongst healthcare professionals (HCPs) before the rollout of a newly developed vaccine in a pandemic setting. The aim of this prospective cohort study was to study the impact of preexisting and prevailing mental health on United Kingdom HCPs’ attitudes towards a newly developed COVID-19 vaccine. Two online surveys were distributed: first during vaccine development (July–September, 2020) and second during nationwide vaccine rollout (December 2020–March 2021). Mental health (PHQ-9 for depression; GAD-7 for anxiety) was assessed in both surveys. Negative attitude regarding vaccine safety and vaccine effectiveness was assessed at vaccine rollout. A series of logistic regression models were developed relating mental health (preexisting during vaccine development, ongoing and new-onset during rollout, and changes in symptom severity) to negative vaccine attitudes. In 634 HCPs, the presence of depression and/or anxiety during vaccine development was associated with elevated negative attitude towards vaccine safety (adj. OR 1.74 [95% CI 1.10–2.75], p = .02), but not vaccine effectiveness (1.13 [0.77–1.66], p = .53) at rollout. This was independent of other characteristics: age, ethnicity, professional role, and history of contracting COVID-19. Ongoing depression and/or anxiety (1.72 [1.10–2.69], p = .02) was associated with elevated negative attitude regarding vaccine effectiveness, but not vaccine safety. Worsened combined symptom scores over time were associated with elevated negative vaccine effectiveness attitudes (1.03 [1.00–1.05], p < .05), but not vaccine safety. Overall, adverse mental health can impact on HCPs’ attitudes towards a newly developed vaccine. Further work is required to understand how this translates to vaccine uptake.

show abstract

Willingness to be vaccinated against COVID-19 is equal in individuals with affective disorders and healthy controls

Cited by 2 publications

References 63 publications

COVID-19 vaccination motivation and underlying believing processes: A comparison study between individuals with affective disorder and healthy controls

COVID-19 vaccination motivation and underlying believing processes: A comparison study between individuals with affective disorder and healthy controls

Factors influencing attitudes toward vaccine safety and vaccine effectiveness amongst UK healthcare professionals prior to and at the time of COVID-19 vaccine rollout: Insights from the CoPE-HCP cohort study

Contact Info

Product

Resources

About