Willingness to receive COVID‐19 booster dose and its associated factors in Ghana: A cross‐sectional study

Storph, Rebecca Peniel; Essuman, Mainprice Akuoko; Duku‐Takyi, Ruth; Akotua, Albert; Asante, Samuel; Armah, Richard; Donkoh, Irene Esi; Addo, Prince Anim

doi:10.1002/hsr2.1203

Cited by 7 publications

(8 citation statements)

References 56 publications

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“…Furthermore, our results are comparable to those reported in Chile (88.2%). However, this result contrasts significantly with the situation in Ghana, where only 46.2% of adults have a high intention to be vaccinated (IBV) ( Storph et al, 2023 ). However, a systematic review indicated that the IBV of the booster dose is different from the actual vaccine uptake ( Abdelmoneim et al, 2022 ) .…”

Section: Discussioncontrasting

confidence: 68%

Factors associated with intention to be vaccinated with the COVID-19 booster dose: a cross-sectional study in Peru

Camacho-Neciosup,

Balcazar-Huaman,

Alvarez-Vilchez

et al. 2024

PeerJ

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Introduction The pandemic of COVID-19 continues to impact people worldwide, with more than 755 million confirmed cases and more than 6.8 million reported deaths. Although two types of treatment, antiviral and immunomodulatory therapy, have been approved to date, vaccination has been the best method to control the spread of the disease. Objective To explore factors associated with the intention to be vaccinated with the COVID-19 booster dose in Peru. Material and Methods Cross-sectional study, using virtual and physical surveys of adults with two or more doses of COVID-19 vaccine, where the dependent variable was the intention to be vaccinated (IBV) with the booster dose. We calculated prevalence ratios with 95% confidence intervals, using generalized linear models of the Poisson family with robust varying, determining associations between sociodemographic, clinical, and booster dose perception variables. Results Data from 924 adults were analyzed. The IBV of the booster doses was 88.1%. A higher prevalence was associated with being male (aPR = 1.05; 95% CI [1.01–1.10]), having a good perception of efficacy and protective effect (PR = 3.69; 95% CI [2.57–5.30]) and belonging to the health sector (PR = 1.10; 95% CI [1.04–1.16]). There was greater acceptance of the recommendation of physicians and other health professionals (aPR = 1.40; 95% CI [1.27–1.55]). Conclusions Factors associated with higher IBV with booster dose include male gender, health sciences, physician recommendation, and good perception of efficacy.

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Section: Discussioncontrasting

confidence: 68%

Factors associated with intention to be vaccinated with the COVID-19 booster dose: a cross-sectional study in Peru

Camacho-Neciosup,

Balcazar-Huaman,

Alvarez-Vilchez

et al. 2024

PeerJ

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“…According to Freeman et al [39](2022), there is evidence suggesting that hesitancy is more prevalent among those who identify as female, have lower income levels, and belong to certain ethnic groups. Adverse side effects of the vaccines [9], [13], [15], [26], [28], [30], [32], [42] 8 2 Mistrust in the vaccine [8], [32], [37], [42],[43] 5 3…”

Section: Description Of the Included Studiesmentioning

confidence: 99%

“…Not confident in the safety of the vaccines [7], [26], [30], [44] The significance of demographic analysis is in the provision of valuable information that can inform effective decision-making processes undertaken by governmental bodies and social service organizations [40,41]. Additionally, it aids individuals in comprehending the attributes of a certain population and its potential future transformations, a crucial aspect in informing decision-making processes.…”

Section: Description Of the Included Studiesmentioning

confidence: 99%

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COVID-19 Vaccine Acceptance and Hesitancy in Ghana: A Systematic Review

Akrong,

Hiadzi,

Donkor

et al. 2023

Preprint

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The propensity to accept vaccines and factors that affect vaccine acceptance and hesitancy will determine the overall success of the COVID-19 vaccination program. Therefore, it is essential for countries to understand the factors that influence vaccine acceptance and hesitancy in order to prevent further future shocks, and it is necessary to have a thorough understanding of these factors. This study, as a result, aims to review selected published works in the domain of study and conduct valuable analysis to determine the most influential factors in COVID-19 vaccine acceptance and hesitancy in Ghana. The review also explored the acceptance rate of COVID-19 vaccines in Ghana. We selected published works from 2021 to April 2023 and extracted, analyzed, and summarized the findings based on the key factors that influence COVID-19 vaccine acceptance and hesitancy in Ghana, the acceptance rate in Ghana, the demographic factors that are often examined, and the study approach used to examine these factors. The study found that positive vaccination perception, safety, belief in vaccine efficacy, knowledge of COVID-19, and a good vaccine attitude influence COVID-19 vaccine acceptance in Ghana. The negative side effects of the vaccines, mistrust in the vaccine, lack of confidence in the safety of the vaccines, fear, and spiritual and religious beliefs all played significant roles in the factors influencing COVID-19 vaccine hesitancy. The demographic parameters frequently included in these studies that have a significant impact include educational attainment, gender, religious affiliation, age, and marital status.

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“…If it subsequently proves to be true, vaccination campaigns against both infections can be combined to reduce the total intervention cost; thus, a combination vaccine can be crucial. Moreover, the willingness to receive COVID-19 booster doses is significantly lower than that for primary vaccinations 7 – 10 . Combining influenza vaccines with COVID-19 booster doses might increase uptake of the latter since many populations are accustomed to receiving annual influenza vaccines 11 , 12 .…”

Section: Introductionmentioning

confidence: 97%

An intranasal combination vaccine induces systemic and mucosal immunity against COVID-19 and influenza

Xing,

Hu,

Wang

et al. 2024

npj Vaccines

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Despite prolonged surveillance and interventions, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses continue to pose a severe global health burden. Thus, we developed a chimpanzee adenovirus-based combination vaccine, AdC68-HATRBD, with dual specificity against SARS-CoV-2 and influenza virus. When used as a standalone vaccine, intranasal immunization with AdC68-HATRBD induced comprehensive and potent immune responses consisting of immunoglobin (Ig) G, mucosal IgA, neutralizing antibodies, and memory T cells, which protected the mice from BA.5.2 and pandemic H1N1 infections. When used as a heterologous booster, AdC68-HATRBD markedly improved the protective immune response of the licensed SARS-CoV-2 or influenza vaccine. Therefore, whether administered intranasally as a standalone or booster vaccine, this combination vaccine is a valuable strategy to enhance the overall vaccine efficacy by inducing robust systemic and mucosal immune responses, thereby conferring dual lines of immunological defenses for these two viruses.

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Willingness to receive COVID‐19 booster dose and its associated factors in Ghana: A cross‐sectional study

Cited by 7 publications

References 56 publications

Factors associated with intention to be vaccinated with the COVID-19 booster dose: a cross-sectional study in Peru

Factors associated with intention to be vaccinated with the COVID-19 booster dose: a cross-sectional study in Peru

COVID-19 Vaccine Acceptance and Hesitancy in Ghana: A Systematic Review

An intranasal combination vaccine induces systemic and mucosal immunity against COVID-19 and influenza

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