We present a correspondence between two-dimensional N = (2, 2) supersymmetric gauge theories and rational integrable gl(m|n) spin chains with spin variables taking values in Verma modules. To explain this correspondence, we realize the gauge theories as configurations of branes in string theory and map them by dualities to brane configurations that realize line defects in four-dimensional Chern-Simons theory with gauge group GL(m|n). The latter configurations embed the superspin chains into superstring theory. We also provide a string theory derivation of a similar correspondence, proposed by Nekrasov, for rational gl(m|n) spin chains with spins valued in finite-dimensional representations. A Four-dimensional Chern-Simons theory with gauge supergroup from twisted string theory 51 A.1 Topological strings 52 A.2 Topological open string field theory 53 A.3 Twisted closed string field theory 55 A.4 Closed-open map 56 A.5 Four-dimensional Chern-Simons theory with gauge supergroup from the SU(3)-invariant twist of type IIB string theory 58