This research investigates the potential of a game-theoretic-based Active Yaw Control (AYC) strategy to enhance power generation in wind farms. The proposed AYC strategy in this study replaces traditional look-up tables with a trained Artificial Neural Network (ANN) that determines the optimal yaw misalignment for turbines under time-varying atmospheric conditions. The study examines a hypothetical 3x2 rectangular arrangement of NREL 5-MW wind turbines. The FAST.Farm simulation tool, utilizing the dynamic wake meandering (DWM) model, is employed to assess both the power performance and structural load on the wind turbines. When tested with two different inflow directions and ambient turbulence (10%), the AYC strategy demonstrated a maximum increase in total power output of 2.6%, although it affected individual turbines differently. It also exhibits an increase in some structural loads, such as tower-top torque, while some components experience a slight reduction in load. The results underscore the effectiveness of the ANN-guided game-theoretic algorithm in improving wind farm power generation by mitigating the negative impact of wake interference, offering a scalable and efficient method for optimizing large-scale wind farm. However, it is essential to evaluate the overall impact of AYC on wind farm efficiency in terms of both Annual Energy Production (AEP) and structural loading under various atmospheric conditions.