In this paper, the method of harmonic suppression and torque ripple reduction is studied for the structure characteristics and design requirements of a high-speed permanent magnet spindle motor. According to the magnetic circuit analysis and calculation theory of the permanent magnet synchronous motor (PMSM), magnetic reluctance slots are arranged at the two ends of the rotor yoke to change the external magnetic field distribution of the permanent magnet in order to optimize the air gap magnetic density waveform. To obtain air gap flux density waveforms that are close to a sinusoidal distribution and not destroy the permanent magnet under the pre-pressure, several reluctance slots with different widths and depths arranged at two ends of the rotor yoke are used to achieve the sinusoidal distribution. Based on the selection of the pole-slot proportion, skewed-slot and a decrease in the end effect, the effects of the harmonic suppression of the harmonic electromotive force (EMF) and the reduction in the torque ripple are discussed. It is concluded that the additional loss and torque ripple of the high-speed permanent magnet spindle motor can be reduced through a reasonable design.