Wireless Capsule Endoscopy: Indications, Limitations, and Future Challenges

El‐Matary, Wael

doi:10.1097/01.mpg.0000304447.69305.cc

Cited by 56 publications

(53 citation statements)

References 96 publications

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“…Although some serious causes are identified in such patients, CE is mostly unyielding. If patients with other signs and symptoms of inflammation were selected, than the diagnostic yield was considerably higher [62] . Capsule endoscopy may be helpful in the diagnosis of the following diseases: surveillance for NSAID side effects, Henoch-Schönlein purpura, indeterminate colitis, protein losing enteropathy, intestinal lymphangiectasia, Meckel's diverticulum, follow-up of SB transplantation, GVHD, and bowel changes in refractory pouchitis [1][2][3][4][5][6][7][8][9][10]62] .…”

Section: Other Indicationsmentioning

confidence: 99%

Five years’ experience with capsule endoscopy in a single center

Kav¹,

Bayraktar²

2009

WJG

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Capsule endoscopy (CE) is a novel technology that facilitates highly effective and noninvasive imaging of the small bowel. Although its efficacy in the evaluation of obscure gastrointestinal bleeding (OGIB) has been proven in several trials, data on uses of CE in different small bowel diseases are rapidly accumulating in the literature, and it has been found to be superior to alternative diagnostic tools in a range of such diseases. Based on literature evidence, CE is recommended as a first-line investigation for OGIB after negative bidirectional endoscopy. CE has gained an important role in the diagnosis and follow-up of Crohn's disease and celiac disease and in the surveillance of small bowel tumors and polyps in selected patients. Capsule retention is the major complication, with a frequency of 1%-2%. The purpose of this review was to discuss the procedure, indications, contraindications and adverse effects associated with CE. We also review and share our five-year experience with CE in various small bowel diseases. The recently developed balloon-assisted enteroscopies have both diagnostic and therapeutic capability. At the present time, CE and balloon-assisted enteroscopies are complementary techniques in the diagnosis and management of small bowel diseases.

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Section: Other Indicationsmentioning

confidence: 99%

Five years’ experience with capsule endoscopy in a single center

Kav¹,

Bayraktar²

2009

WJG

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“…There are major challeng es to the expansion of capsule technology into a position where it can compete with conventional diagnostic gastroscopy and colonoscopy [1][2][3][4][5] . The first challenge is power management.…”

Section: Introductionmentioning

confidence: 99%

The future of wireless capsule endoscopy

Swain¹

2008

WJG

146

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We outline probable and possible developments with wireless capsule endoscopy. It seems likely that capsule endoscopy will become increasingly effective in diagnostic gastrointestinal endoscopy. This will be attractive to patients especially for cancer or varices detection because capsule endoscopy is painless and is likely to have a higher take up rate compared to conventional colonoscopy and gastroscopy. Double imager capsules with increased frame rates have been used to image the esophagus for Barrett's and esophageal varices. The image quality is not bad but needs to be improved if it is to become a realistic substitute for flexible upper and lower gastrointestinal endoscopy. An increase in the frame rate, angle of view, depth of field, image numbers, duration of the procedure and improvements in illumination seem likely. Colonic, esophageal and gastric capsules will improve in quality, eroding the supremacy of flexible endoscopy, and become embedded into screening programs. Therapeutic capsules will emerge with brushing, cytology, fluid aspiration, biopsy and drug delivery capabilities. Electrocautery may also become possible. Diagnostic capsules will integrate physiological measurements with imaging and optical biopsy, and immunologic cancer recognition. Remote control movement will improve with the use of magnets and/or electrostimulation and perhaps electromechanical methods. External wireless commands will influence capsule diagnosis and therapy and will increasingly entail the use of real-time imaging. However, it should be noted that speculations about the future of technology in any detail are almost always wrong.

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“…Although some serious causes are identified in such patients, CE is mostly unyielding. If patients with other signs and symptoms of inflammation were selected, than the diagnostic yield was considerably higher (El-Matary, 2008). Capsule endoscopy may be helpful in the diagnosis of the following diseases: surveillance for NSAID side effects, Henoch Schönlein purpura, indeterminate colitis, protein losing enteropathy, intestinal lymphangiectasia, Meckel's diverticulum, follow-up of SB transplantation, GVHD, and bowel changes in refractory pouchitis (El-Matary,2008).…”

Section: Other Indicationsmentioning

confidence: 99%