The current journal paper proposes an end-to-end analysis for the numerical implementation of a two-degrees-of-freedom (2DOF) control structure, starting from the sampling rate selection mechanism via a quasi-optimal manner, along with the estimation of the worst-case execution time (WCET) for the specified controller. For the sampling rate selection, the classical Shannon–Nyquist sampling theorem is replaced by an optimization problem that encompasses the trade-off between the fidelity of the controllers’ representation, along with the fidelity of the resulting closed-loop systems, and the implementation difficulty of the controllers. Additionally, the WCET analysis can be seen as a verification step before automatic code generation, a computational model being provided. The proposed computational model encompasses infinite-impulse response (IIR) and finite-impulse response (FIR) filter models for the controller implementation, along with additional relevant phenomena being discussed, such as saturation, signal scaling and anti-windup techniques. All proposed results will be illustrated on a DC motor benchmark control problem.