2023
DOI: 10.36227/techrxiv.22223335
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Wireless Monitoring of Small Molecules in a Freely Moving Animal using Electrochemical Aptamer Biosensors

Abstract: <p>This paper introduces a wireless electro- chemical sensing system for in vivo small-molecule sensing using reagent-less structure-switching aptamers. The system consists of a 65-nm CMOS electrochemical sensing circuit with an on-chip waveform generator, a Bluetooth microcontroller (MCU), and a battery, which allow for robust wireless recording in a freely moving animal. The device can perform data acquisition every 10 seconds, including wireless data transfer, and consumes an average current of 3mA af… Show more

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