Wirkung des D-Vitamins am nebenschilddrüsenexstirpierten Hund

Treatment of Postoperative Parathyroid Insufficiency

“…Demole and Christ (1929) confirmed the value of irradiated ergosterol in the control of tetany following thyroparathyroidectomy on dogs. Brougher also reported good results when this substance was administered in con¬ junction with calcium lactate in the form of milk; he emphasized the necessity of a regular supply of calcium and pointed out that if the dog did not retain the milk, tetany developed.…”

The Antirachitic Action of Cod Liver Oil and Irradiated Ergosterol in Parathyroidectomized and Thymectomized Rats

“…The observations have been somewhat conflicting. Whereas Brougher (1), Wade (2), and more recently, Jones, Rapoport and Hoden (3), and Demole and Christ (4), were able to mitigate the symptoms of tetany, to prolong life, and to bring about an elevation of blood calcium after parathyroidectomy, Urechiu and Popoviciu (5), and Greenwald and Gross (6), were unable to demonstrate such effects. Wade found that the preoperative administration of cod liver oil mitigated symptoms and prolonged life, but did not prevent a fall in the blood calcium.…”