Fossil pollen, plant macrofossils, gastropods, and elemental and stable-isotope geochemistry in a sediment core from Twiss Marl Pond, southern Ontario, Canada, were used to document climate oscillations during the Last Glacial}Interglacial transition ( &13,000}8500 C BP) and understand their ecological e!ects. Chronology was provided by AMS C dating and regional pollen correlation. Oxygen isotope ( O) results from mollusc shells, Chara-encrustations and bulk carbonates show a classic climate sequence of a warm B+lling}Aller+d (BOA) at &12,500}10,920 C BP, a cold Younger Dryas (YD) at 10,920}10,000 C BP, the Holocene warming at 10,000 C BP, a brief Preboreal Oscillation (PB) at 9650 C BP, and a possible Gerzensee/Killarney (G/K) cooling shortly before 11,000 C BP.Clay sediments at the base of the core contain high herb and shrub pollen and abundant arctic/alpine plant macrofossils, indicating a treeless tundra with severe soil erosion in watershed. During the BOA warm period, authigenic marl began to be deposited, and Picea woodland became established. The establishment of Picea woodland after peaks of O and of carbonate accumulation suggests a lagged response of upland vegetation to BOA warming. In contrast, the occurrence of warmth-loving aquatics Najas yexilis and Typha latifolia at that time indicates sensitive responses of aquatic plants. The YD cooling is indicated by a &1.5 negative excursion in O, an increase in minerogenic matter and higher concentrations of erosion-derived elements (Al, Na, K, Ti and V). Pollen data show no forest transformation in response to YD cooling, which is attributed to the insensitive nonecotonal vegetation at that time. However, more openings in the forests and increased erosion in the watershed are indicated by a slight increase of herb pollen, high concentrations of erosion elements and a Pediastrum peak. The onset of the Holocene was marked by an abrupt increase of 2 in O and the replacement of Picea woodland by Pinus-dominated forest. The Picea recurrence at 9650 C BP demonstrates sensitive response of ecotonal vegetation to the PB climate oscillation, which is also indicated by 0.4 negative excursion of O. These new results suggest the importance of multiproxy records for reliable paleoclimate reconstruction.Reevaluation and revised chronologies of previously published sites (Gage Street, and Nichols Brook) in the eastern Great Lakes region show their major O shifts correlative to the YD and PB oscillations as documented from Twiss Marl Pond and nearby Crawford Lake. The sequence and magnitude of climatic oscillations from these sites match in detail with records from the Atlantic Seaboard, suggesting that these oscillations are an expression of broad-scale, probably global, climate change rather than local meltwater-induced climate cooling.