Wisteria floribunda lectin is associated with specific cell types in the ventral cochlear nucleus of the gerbil, Meriones unguiculatus

Topographical and cellular distribution of perineuronal nets in the human cochlear nucleus

“…In the DCN, we observed few neurons with perineuronal nets. In the gerbil DCN, few neurons are associated with perineuronal nets, but in the rhesus DCN a ''homogenous distribution pattern" was observed (gerbil - Cant and Benson, 2006;rhesus -Hilbig et al, 2007). The reason for this variation remains unclear.…”

“…Perineuronal nets have been associated with fast-spiking, paravalbumin-immunoreactive neurons in the rhesus amygdala and it has been suggested that perineuronal nets may function in the processing of high-frequency auditory stimuli (Hartig et al, 1995;Hilbig et al, 2007). Cant and Benson (2006) make the intriguing correlation of projection target with perineuronal nets in the gerbil CN. So, perineuronal nets have been associated with a number of specific neuronal populations across a number of species, but what exactly dictates why some neurons are associated with perineuronal nets and others are not remains unclear.…”

“…However, despite the detailed descriptions of the CN in laboratory animals many questions remain regarding organization of this complex region and the distribution of specific cell types in human (Bacsik and Strominger, 1973;Konigsmark, 1969;Moore and Osen, 1979). Moreover, perineuronal nets have been associated with specific neuronal subtypes in auditory nuclei in rats, gerbils and rhesus (Hartig et al, 2001;Cant and Benson, 2006;Hilbig et al, 2007). Thus, the goal of this study is to use histochemical techniques to map the distribution of perineuronal nets and associate these specializations of the ECM with specific populations within the human CN.…”

Distribution of perineuronal nets in the human superior olivary complex

“…Recently, it has been shown that environmental enrichment during the early post-natal period expedites the development of PNN in contextually dependant regions of the brain (Simonetti et al, 2009). PNNs can be positively identified via numerous histo-and immunocytochemical techniques, but are only associated with specific neuronal populations and comparative studies provide evidence indicating speciesspecific distributions of PNNs (Nakagawa et al, 1986;Brückner et al, 1993;Wintergerst et al, 1996;Atoji et al, 1997;Celio et al, 1998;Morris and Henderson, 2000;Härtig et al, 2001;Cant and Benson, 2006;Deepa et al, 2006;Hilbig et al, 2007;Pantazopoulos et al, 2008;Wagoner and Kulesza, 2009;Morawski et al, 2009).…”

“…PNNs have been associated with specific neuronal subtypes in the auditory brainstem nuclei of rat, gerbil, hedgehog, dog, rhesus and human (rat -Friauf, 2000;Härtig et al, 2001;gerbil -Lurie et al, 1997;Cant and Benson, 2006;hedgehog -Morawski et al, 2009;dog -Atoji and Suzuki, 1992;Atoji et al, 1990Atoji et al, , 1995Atoji et al, , 1997rhesus -Hilbig et al, 2007;human -Wagoner and Kulesza, 2009). Furthermore, we recently reported that PNNs are restricted to select populations of neurons within the human ventral cochlear nucleus (VCN).…”