With new prenatal testing, will babies with Down syndrome slowly disappear?

Skotko, Brian G.

doi:10.1136/adc.2009.166017

Cited by 75 publications

(52 citation statements)

References 40 publications

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“…Undoubtedly, all stakeholders should participate in deciding what tests are available and how both management and counseling of pregnant women should be addressed. 12,32,33 A limitation of this study is the need to make certain assumptions about NIPD to predict its impact. These assumptions relate to the robustness and accuracy of the test, and the choices that women will make if NIPD replaces screening tests, especially with regard to women currently having no testing and continuing to have no testing.…”

Section: Discussionmentioning

confidence: 99%

Using population-based data to predict the impact of introducing noninvasive prenatal diagnosis for Down syndrome

Susman

Amor

Muggli

et al. 2010

Genetics in Medicine

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Section: Discussionmentioning

confidence: 99%

Using population-based data to predict the impact of introducing noninvasive prenatal diagnosis for Down syndrome

Susman

Amor

Muggli

et al. 2010

Genetics in Medicine

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“…Related to this point, Skotko warns that promoting "choice" as medical progress in the context of prenatal screening may lead to the "disappearance" of people with Down syndrome [52]. Skotko's argument is important to consider in light of termination statistics from around the world.…”

Section: A New-genics? the Example Of Down Syndromementioning

confidence: 99%

Keeping the Backdoor to Eugenics Ajar?: Disability and the Future of Prenatal Screening

Thomas

Rothman

2016

AMA Journal of Ethics

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“…The question has already been raised as to whether trends in prenatal screening and diagnosis are likely to translate into the disappearance of births with Down syndrome 30 . The decline in the number of children born with disabilities may lead to subtle changes in public attitudes about the handicapped and their families.…”

Section: Ethical Issuesmentioning

confidence: 99%

Untitled

2013

IJPSR

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Aneuploidies are one of the important causes of perinatal morbidity and mortality. Initially screening for aneuploidies started with maternal age risk estimation. Later on, serum testing for biochemical markers and ultrasound markers were added. Women detected to be at high risk for aneuploidies were offered invasive testing. Recently, various methods including non-invasive prenatal testing (NIPT) by analysis of cell-free fetal DNA (cffDNA) in maternal blood has shown promise for highly accurate detection of common fetal autosomal trisomies. Incorporating these new noninvasive technologies into clinical practice will impact the current prenatal screening paradigm for fetal aneuploidy, in which genetic counseling plays an integral role. The advantage of the technique being elimination of risks such as miscarriage associated with invasive diagnostic procedures. But then this new technique has its own set of technical limitations and ethical issues at present and further research is required before implementation. Data was obtained through a literature search via Pubmed and Google as well as detailed search of our library database.

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With new prenatal testing, will babies with Down syndrome slowly disappear?

Cited by 75 publications

References 40 publications

Using population-based data to predict the impact of introducing noninvasive prenatal diagnosis for Down syndrome

Using population-based data to predict the impact of introducing noninvasive prenatal diagnosis for Down syndrome

Keeping the Backdoor to Eugenics Ajar?: Disability and the Future of Prenatal Screening

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