WITHDRAWN: Assessment Parameters on Array Pulse Wave Analysis and Application in Hypertensive Disorders

Abstract

Background: At present, there is no effective analysis method for array pulse wave. But this is very important for promoting the development of pulse diagnosis. Hypertension is a common and easy-to-diagnosis of cardiovascular disease, which is the development foundation of other cardiovascular diseases. Our goal in the study is to establish analysis method for array pulse wave and preliminary application in hypertensive disorders.Methods: In this study, a sensor array can be used for real-time monitoring of pulse wave twelve channels. We calculated the average pulse wave (APW) of per channel within thirty seconds. The most representative pulse wave (MRPV) and the APW matched by correlation coefficient. Feature points of the MRPV were identified by manually. These feature points corresponding to the array pulse volume (APV) parameters were also identified by manually. Finally, clinical trial was executed to detect these feature performance indicators in hypertensive disorders.Results: The raoAPV h1 , raoAPV h3 , raoAPV h4 , raoAPV h3/h1 and raoAPV h4/h of hypertension group significantly increased compared with that of the healthy group ( P <0.01, P <0.05). The zhongAPV h4 , zhongAPV h3/h1 , zhongAPV h4/h1 and meanAPV h3 , meanAPV h3/h1 , meanAPV h4/h1 were significantly increased in hypertension group compared with healthy group ( P <0.05, P <0.01). The chiAPV h4/h1 of hypertension group was obviously elevated ( P <0.05). The results preliminarily validated novelty of APV on array pulse wave analysis. This indicator was effective in reflecting the hypertensive vascular function.Conclusion: Traditional Chinese Medicine (TCM) pulse is a combination of multi-dimensional information. Array sensor could be better reduction of TCM pulse characteristics. In the study, the analysis of array pulse wave was valid, and the APV was reliable to mirror TCM pulse characteristics. Keywords ： Pulse diagnosis; Traditional Chinese medicine; Sensor array; Array pulse volume; Healthy persons; Hypertension persons.

Assessment Parameters for Arrayed Pulse Wave Analysis and Application in Hypertensive Disorders

“…In addition, an earlier version of this manuscript has been stored on the preprint server, and the link is as follows https://www.researchsquare.com/article/rs-126124/v1 . [ 39 ].…”