WITHDRAWN: Role of Cardiovascular Color Doppler Imaging Information Technology Under Artificial Intelligence Neural Network in the Diagnosis of Septic Shock Patients

Shen, Hualiang; Hu, Yinfeng; Liu, Xiatian; Jiang, Zhenzhen; Ye, Hongwei

doi:10.1016/j.neulet.2020.135199

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…However, whether long-term environmental exposure to such environmental estrogens causes changes in cardiac function and structure urgently needs to be investigated. Cardiac Doppler ultrasound is widely used for cardiac evaluation and examination in the clinic, and is an important tool for the detection of the cardiac structure and function [16]. Whether the structure and function of the left ventricle of the heart is affected can be assessed with the help of Doppler ultrasound.…”

Section: Introductionmentioning

confidence: 99%

Effects of Long-term Nonylphenol Exposure on Myocardial Fibrosis and Cardiac Function in Rats

Liu

et al. 2021

Preprint

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Background: Myocardial fibrosis is a critical pathological basis for the poor prognosis of cardiovascular diseases. Studies have found that myocardial fibrosis is closely associated with exposure to environmental estrogens such as nonylphenol (NP), as a representative of environmental estrogens. The aim of this study was to examine the effects of NP chronic exposure on myocardial fibrosis as well as cardiac structure and function. Forty Sprague Dawley rats were randomly divided into four groups (n = 10): control group (C), low NP dose (0.4 mg/kg, L), medium NP dose (4 mg/kg, M), and high NP dose (40 mg/kg, H) groups. The NP dose groups were gavaged with NP for 180 days. Results: The NP level in the heart of the NP groups was significantly higher than those in the control group (F = 43.658, P < 0.001). Serum aspartate aminotransferase (AST), creatine kinase (CK), creatine kinase isozyme (CK-MB), lactate dehydrogenase (LDH) and α-hydroxybutyrate dehydrogenase (α-HBDH) significantly increased in the NP groups compared with the control group (). Histopathological examination of the heart biopsy illustrates that in the medium and high NP groups, the fibrous connective tissue had a disordered and loose gridding shape, muscle fibers had fractured, and muscle fibers were loose with a widened gap. Extensive inflammatory cell infiltration and fibroblast proliferation in the myocardial interstitium were also found. With increasing NP dose, the degree of muscle fiber loosing and disorder became more significant in the NP treatment groups, and the collagen volume fraction (CVF) was higher than that in the control group (P < 0.01). Compared with the control group, the expression of collagen I and collagen III increased significantly in the medium and high NP groups (P < 0.05). The values of the systolic thickness of the left ventricular anterior wall (LVAWs), the diastolic thickness of the left ventricular posterior wall (LVPWd), the systolic thickness of the left ventricular posterior wall (LVPWs), and the left ventricular anterior wall (LVAWd) in the NP groups are were slightly lower than those in of the control group. The values of left ventricular end systolic dimensions (LVIDs) in the NP groups increased compared with the control group. Conclusions: Long-term NP exposure could lead to fibrosis in the rat myocardium, which is characterized by increased expressions of myocardial collagen I and collagen III, as well as elevated cardiac enzymes. In addition, the cardiac structure was affected and changes were observed in the thinner ventricular wall and as an enlarged ventricular cavity.

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Section: Introductionmentioning

confidence: 99%

Effects of Long-term Nonylphenol Exposure on Myocardial Fibrosis and Cardiac Function in Rats

Liu

et al. 2021

Preprint

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“…22 The purpose of the study was to analyse the effect of cardiovascular color doppler ultrasound imaging on application of artificial intelligence neural network in the diagnosis of septic shock (Shen et al, 2020).…”

Section: Artificial Intelligencementioning

confidence: 99%

Meta-Analysis of EMF-Induced Pollution by COVID-19 in Virtual Teaching and Learning With an Artificial Intelligence Perspective

Das¹,

Srivastava²,

Tripathi³

2021

International Journal of Web-Based Learning and Teaching Technologies

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Concerns about the health effects of frequent exposure to electromagnetic fields (EMF) emitted from mobile towers and handsets have been raised because of the gradual increase in usage of cell phones and frequent setting up of mobile towers. Present study is targeted to detrimental effects of EMF radiation on various biological systems mainly due to online teaching and learning process by suppressing the immune system. During COVID-19 pandemic the increased usage of internet due to online education and online office leads to more detrimental effects of EMF radiation. Further inculcation of soft computing techniques in EMF radiation has been presented. A literature review focusing on the usage of soft computing techniques in the domain of EMF radiation has been presented in the article. An online survey has been conducted targeting Indian academic stakeholders’ (Specially Teachers, Students and Parents termed as population in paper) for analyzing the awareness towards the bio hazards of EMF exposure.

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“…Cardiac Doppler ultrasound is widely used for cardiac evaluation and examination in the clinic, and is an important tool for the detection of the cardiac structure and function [18]. Whether the structure and function of the left ventricle of the heart is affected can be assessed with the help of Doppler ultrasound.…”

Section: Introductionmentioning

confidence: 99%

Effects of long-term nonylphenol exposure on myocardial fibrosis and cardiac function in rats

Liu

et al. 2021

Environ Sci Eur

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Background Myocardial fibrosis is a critical pathological basis for the poor prognosis of cardiovascular diseases. Studies have found that myocardial fibrosis is closely associated with exposure to environmental estrogens such as nonylphenol (NP), as a representative of environmental estrogens. The aim of this study was to examine the effects of NP chronic exposure on myocardial fibrosis as well as cardiac structure and function. Forty Sprague–Dawley rats were randomly divided into four groups (n = 10): control group (C), low NP dose (0.4 mg/kg, L), medium NP dose (4 mg/kg, M), and high NP dose (40 mg/kg, H) groups. The NP dose groups were gavaged with NP for 180 days. Results The NP level in the heart of the NP groups was significantly higher than those in the control group (F = 43.658, P < 0.001). Serum aspartate aminotransferase (AST), creatine kinase (CK), creatine kinase isozyme (CK-MB), lactate dehydrogenase (LDH) and α-hydroxybutyrate dehydrogenase (α-HBDH) significantly increased in the NP groups compared with the control group (P < 0.05). Histopathological examination of the heart biopsy illustrates that in the medium and high NP groups, the fibrous connective tissue had a disordered and loose gridding shape, muscle fibers had fractured, and muscle fibers were loose with a widened gap. Extensive inflammatory cell infiltration and fibroblast proliferation in the myocardial interstitium were also found. With increasing NP dose, the degree of muscle fiber loosing and disorder became more significant in the NP-treatment groups, and the collagen volume fraction (CVF) was higher than that in the control group (P < 0.01). Compared with the control group, the expression of collagen I and collagen III increased significantly in the medium and high NP groups (P < 0.05). The values of the systolic thickness of the left ventricular anterior wall (LVAWs), the diastolic thickness of the left ventricular posterior wall (LVPWd), the systolic thickness of the left ventricular posterior wall (LVPWs), and the left ventricular anterior wall (LVAWd) in the NP groups are were slightly lower than those in of the control group. The values of left ventricular end systolic dimensions (LVIDs) in the NP groups increased compared with the control group. Conclusions Long-term NP exposure could lead to fibrosis in the rat myocardium, which is characterized by increased expressions of myocardial collagen I and collagen III, as well as elevated cardiac enzymes. In addition, the cardiac structure was affected and changes were observed in the thinner ventricular wall and as an enlarged ventricular cavity.

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WITHDRAWN: Role of Cardiovascular Color Doppler Imaging Information Technology Under Artificial Intelligence Neural Network in the Diagnosis of Septic Shock Patients

Cited by 3 publications

References 14 publications

Effects of Long-term Nonylphenol Exposure on Myocardial Fibrosis and Cardiac Function in Rats

Effects of Long-term Nonylphenol Exposure on Myocardial Fibrosis and Cardiac Function in Rats

Meta-Analysis of EMF-Induced Pollution by COVID-19 in Virtual Teaching and Learning With an Artificial Intelligence Perspective

Effects of long-term nonylphenol exposure on myocardial fibrosis and cardiac function in rats

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