Within-herd spread of contagious bovine pleuropneumonia in Ethiopian highlands

Lesnoff, Matthieu; Laval, Géraud; Bonnet, Pascal; Abdicho, Sintayehu; Workalemahu, Asseguid; Kifle, Daniel; Peyraud, Armelle; Lancelot, Renaud; Thiaucourt, François

doi:10.1016/j.prevetmed.2004.03.005

Cited by 27 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The close proximity between small herds and their collective movements (nomadism and trade of livestock) may favor the rapid disease spread through introduction of sick animals in the herds. Indeed, Lesnoff et al (2004) showed that the risk of CBPP spread is quite high in a closed herd even in the presence of an epidemiological surveillance. In any case, these observed results refute the general view that the northern part of the country is free from CBPP.…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali

Séry

Sidibé

Cissé

et al. 2014

Trop Anim Health Prod

Self Cite

View full text Add to dashboard Cite

A serological survey to determine the prevalence of contagious bovine pleuropneumonia (CBPP) in Mali was carried out by using the competitive enzyme linked-immunosorbent test (c-ELISA) on 8007 serum samples systematically collected from 199 cattle herds collected throughout the whole country. Results showed a national prevalence of 18.11 % at the individual level and 85.93 % at the herd level. Significant variations in the individual prevalence were observed between regions of the country and ranged from 4.63 % in Tombouctou to 54.88 % in Kidal. At the herd level, although there were variations between regions, a high prevalence was constantly observed ranging from 60 to 100 %, hence confirming the endemic nature of the disease across the country. The CBPP risk varied also between regions and was very low in Tombouctou (odds ratio (OR) = 0.4) but very high in Kidal (OR = 9.8). Similarly, the risk seemed higher in the animals of the over 3-year age group (OR = 1.6) compared to the other age groups. It was also observed that there was a slightly higher risk (OR = 1.3) in the females than in the males. This study confirms the presence of CBPP across the country and should help to elaborate strategies for the effective control of the disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali

Séry

Sidibé

Cissé

et al. 2014

Trop Anim Health Prod

Self Cite

View full text Add to dashboard Cite

show abstract

“…The use of antibiotics against CBPP has long been controversial, though some earlier studies showed evidence suggesting efficacy in preventing transmission of the disease [13], largely preventing formation of sequestra, which is believed to be the primary source of carrier status [11] and reduction in clinical cases and death after treatment [9, 14]. There have also been some studies and pronouncements that have supported the belief that antibiotics lead to chronic carriers [1, 14] and found no evidence that antibiotic treatment reduced case fatality risk and average duration of clinical signs, although the authors speculated that the most widely used medication, a single intramuscular injection of 10–20 ml of 10% oxytetracycline suspension, was unlikely to achieve recovery [15] and has little impact on outcome of clinical cases [15]. Although the drugs would promote clinical alleviation of pain and discomfort in cattle and reduce excretion of Mmm and thus reduce new infections, the need to evaluate the development of antibiotic resistance cannot be overemphasised.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of new generation macrolides for the treatment and metaphylaxis of contagious bovine pleuropneumonia (CBPP) in cattle experimentally infected with Mycoplasma mycoides subspecies mycoides

et al. 2019

View full text Add to dashboard Cite

BackgroundContagious bovine pleuropneumonia (CBPP) caused by Mycoplasma mycoides subspecies mycoides (Mmm) is an important disease of cattle that causes serious economic losses. With the known effectiveness of new generation macrolides, tulathromycin and gamithromycin were assessed in comparison with oxytetracycline as a positive control and saline as a negative control for effectiveness in inhibiting lung lesion development, promoting resolution, preventing spread and bacteriological clearance in susceptible local cattle breeds in two separate studies in Kenya and Zambia. Animals were monitored for clinical signs, sero-conversion as well as detailed post-mortem examination for CBPP lesions.ResultsUsing the Hudson and Turner score for lesion type and size, tulathromycin protected 90%, gamithromycin 80%, and oxytetracycline 88% of treated animals in Kenya. In Zambia, all animals (100%) treated with macrolides were free of lung lesions, while oxytetracycline protected 77.5%. Using the mean adapted Hudson and Turner score, which includes clinical signs, post-mortem findings and serology, tulathromycin protected 82%, gamithromycin 56% and oxytetracycline 80% of the animals in Kenya whereas in Zambia, tulathromycin protected 98%, gamithromycin 94% and oxytetracycline 80%. The saline-treated groups had 93 and 92% lesions in Kenya and Zambia respectively, with Mmm recovered from 5/14 in Kenya and 10/13 animals in Zambia. Whereas the groups treated with macrolides were free from lesions in Zambia, in Kenya 5/15 tulathromycin-treated animals and 6/15 gamithromycin-treated animals showed lesions. Oxytetracycline-treated animals showed similarities with 3/14 and 4/15 showing lesions in Zambia and Kenya respectively and Mmm recovery from one animal in Kenya and six in Zambia. In both studies, lesion scores of saline-treated groups were significantly higher than those of the antibiotic treated groups (p < 0.001). In sentinel animals, CBPP lesions were detected and Mmm recovered from one and two animals mixed with the saline-treated groups in Kenya and Zambia respectively.ConclusionsThis study demonstrated that tulathromycin, a mycoplasmacidal, can achieve metaphylactic protection of up to 80%, while non-recovery of Mmm from sentinels suggests macrolides effectiveness in preventing spread of Mmm. It is recommended that further studies are conducted to evaluate strategies comparing vaccination alone or combining vaccination and antibiotics to control or eradicate CBPP.

show abstract

“…No recorded document as to when and how the CBPP exactly entered to Ethiopia (Amanfu, 2009) and it is an important economic disease (Thomson., 2005). CBPP is endemic in Eastern Africa including Ethiopia (Lesnoff et al., 2004). The highest number of outbreaks reported in 20 African countries was recorded in Ethiopia according to OIE (OIE., O.I.D.E., 2008).…”

Section: Introductionmentioning

confidence: 99%

Contagious bovine pleuropneumonia: Seroprevalence and its associated risk factors in selected districts of Afar region, Ethiopia

Negash

Dubie

2021

Veterinary Medicine & Sci

View full text Add to dashboard Cite

Background In pastoral and lowland areas of the country particularly in Afar region, studies suggested higher prevalence of contagious bovine pleuropneumonia (CBPP) than mid and highland agro‐ecologies. Though CBPP is a prime constraint to cattle productivity in the region, research outputs pertaining to CBPP are unavailable compared to highland areas. Thus, the objectives of the current study were to determine seroprevalence of CBPP and assess risk factors in selected districts of Afar region. Methods A cross‐sectional study was conducted on cattle aged 6 months and above from February 2018 to January 2019 in selected districts of the region. A total of 420 blood samples were collected and sera were separated for further serologic analysis. Using competitive enzyme linked immunosorbent assay (c‐ELISA), antibodies against Mycoplasma mycoides subspecies mycoides small colony (MmmSc) were detected at National Veterinary Institute, Ethiopia. Data were analysed using Stata version 14.0. Result Of 420 samples tested by c‐ELISA, 158 samples were found to be positive for CBPP providing an overall seroprevalence of 37.6%. Among the three risk factors considered (age, sex and district) assessed, only two (age and district) were found to be associated significantly with the disease (p < 0.05) at 95% CI and p‐value less than 5% applying logistic regression. Conclusion The study has revealed a higher prevalence of CBPP over the study areas urging a coordinated act to be set in place.

show abstract

Within-herd spread of contagious bovine pleuropneumonia in Ethiopian highlands

Cited by 27 publications

References 24 publications

Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali

Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali

Evaluation of new generation macrolides for the treatment and metaphylaxis of contagious bovine pleuropneumonia (CBPP) in cattle experimentally infected with Mycoplasma mycoides subspecies mycoides

Contagious bovine pleuropneumonia: Seroprevalence and its associated risk factors in selected districts of Afar region, Ethiopia

Contact Info

Product

Resources

About