Utilizing the large quantity of hyperons and antihyperons produced by the decay of 10 billion [Formula: see text] and 2.7 billion [Formula: see text] collected at BESIII, the cross-sections of several specific elastic or inelastic (anti-)hyperon–nucleus/nucleon reactions have been measured via the scattering between the (anti-)hyperons and the nucleus in the dense objects of BESIII detector. The novel method developed in these works extends the research field and opens a new era for the experiments at [Formula: see text] colliders. The results of such measurements will definitely benefit a lot the precise probe of the (anti-)hyperon–nucleus/nucleon interactions and provide constraints for the studies of the potential of strong interaction, the origin of color confinement, the unified model for baryon–baryon interactions, and the internal structure of neutron stars. The desirable prospects of corresponding studies in the future Super Tau-Charm Factory (STCF) are also discussed in this report.