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Abstract

This study shows the testicular assessment of Abelmoschus esculentus treated animals. Twenty-one animals weighing between 100g-120g were grouped into three groups, seven animals for each group. The rats in group A served as the control and fed with normal rat chew and water while the animals in group B treated with 1.0mg/ KgBw and C 3.0 mg/KgBw aqueous extract of Abelmoschus esculentus orally for 14 days. All the animals were sacrificed a day after the administration and the testes removed for histological tissues processing using Hematoxylin and Eosin (H&E) stain. The caudal part of the epididymis was harvested for collection of semen for analysis. Result of the study shows a significant (p<0.05) increase in final body weight of all the animals compared with their initial body weight while result from semen analysis shows a significant increase (p<0.05) in percentage sperm motility in the control and high dose group, the highest percentage of sperm morphology was observed in the control group while the sperm vitality reveals a significant decrease (p<0.05) in the low dose and high dose. Results of the histology of the control group showed a normal histology of the seminiferous tubules (round cells), low dose showed seminiferous tubules with acute loss of Germinal cell area (G) and high dose showed testicular regression (loss of interstitial space, IT), tubular architecture and Germ layer (G).