2018
DOI: 10.2147/ppa.s171348
|View full text |Cite
|
Sign up to set email alerts
|

Women’s preferences, willingness-to-pay, and predicted uptake for single-nucleotide polymorphism gene testing to guide personalized breast cancer screening strategies: a discrete choice experiment

Abstract: BackgroundSingle-nucleotide polymorphism (SNP) gene test is a potential tool for improving the accuracy of breast cancer risk prediction. We seek to measure women’s preferences and marginal willingness-to-pay (mWTP) for this new technology.Materials and methodsWe administered a discrete choice experiment (DCE) to English-speaking Singaporean women aged 40–69 years without any history of breast cancer, enrolled via door-to-door recruitment with quota sampling by age and ethnicity. DCE attributes comprise: 1) sa… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

3
40
1

Year Published

2020
2020
2024
2024

Publication Types

Select...
8
1
1

Relationship

3
7

Authors

Journals

citations
Cited by 16 publications
(44 citation statements)
references
References 53 publications
3
40
1
Order By: Relevance
“…Most notably, cost-effectiveness analyses have been performed to assess the monetary and health benefits of incorporating PRSes in age-based population screening programmes. Many of these support a risk-based approach over current methods based on its cost-effectiveness and reduction of overdiagnosis, while retaining screening benefits [ 15 , 18 20 ]. Large-scale trials such as WISDOM [ 21 ] and PROCAS [ 22 ] have been commenced in order to determine the impact of PRSes in population screening approaches.…”
Section: Introductionmentioning
confidence: 99%
“…Most notably, cost-effectiveness analyses have been performed to assess the monetary and health benefits of incorporating PRSes in age-based population screening programmes. Many of these support a risk-based approach over current methods based on its cost-effectiveness and reduction of overdiagnosis, while retaining screening benefits [ 15 , 18 20 ]. Large-scale trials such as WISDOM [ 21 ] and PROCAS [ 22 ] have been commenced in order to determine the impact of PRSes in population screening approaches.…”
Section: Introductionmentioning
confidence: 99%
“…The aims of BREATHE are aligned with efforts to use personalized health for tailored interventions. For breast cancer screening, multiple studies have supported a risk-stratified approach over the current age-based paradigm due to potentially higher cost-effectiveness and reduced over-diagnosis [ 13 , 24 , 53 , 54 ]. If BREATHE is successful, women will gain a realistic understanding of their personal risk of breast cancer as well as strategies to reduce their risk, and fewer women will suffer from the anxiety of false positive mammograms and unnecessary biopsies.…”
Section: Discussionmentioning
confidence: 99%
“…Other important socio-demographic factors associated with WTP for genetic testing were gender, marital status, total monthly household income, and education level. From the literature, WTP generally rose with income [27][28][29][30][31]. Moreover, women are typically found to be more anxious about health than men [25].…”
Section: Discussionmentioning
confidence: 99%