Over the last two decades, menstrual health and hygiene have become increasingly common on the global health agenda. While governments and international organizations are adopting measures to make menstrual products more accessible, corporate actors producing them have only been subject to limited scrutiny. Yet, their products and commercial practices raise environmental, health, equity and societal issues, which warrant attention and regulation. As such, commercial disposable menstrual products are largely made up of plastic, sometimes as much as 90%. Menstrual pads and tampons also contain some chemicals, the health impact of which is still unclear. In addition, these products are often sold with high-profit margins, and marketing campaigns to sell such products tend to reinforce shame and secrecy. So far, no global standards exist to regulate menstrual products and manufacturers, and evidence in the field of menstrual health and hygiene is lagging behind. To fill this gap, countries have started to regulate menstrual products and the International Standards Organization is in the process of developing global standards to better regulate the content and labeling of menstrual products. To support the emergence of regulation in this area, this article conceptualizes for the first time a comprehensive framework for the regulation of menstrual product manufacturers. This framework encompasses five complementary measures to regulate the content; labeling; production and waste management; pricing; advertising and marketing of menstrual products. The article also calls for more research to produce evidence and for increased governmental and inter-governmental attention to menstrual product manufacturers.