Women’s breast cancer risk factors in Kinshasa, Democratic Republic of the Congo

Abstract

Purpose: Breast cancer (BC) is the most common malignancy and the leading cause of cancer-related deaths among women worldwide. Risk factors for this disease are numerous and their prevalence varies according to racial and ethnic groups and geographical regions. Therefore, we sought to identify BC risk factors in the Congolese population. Methods: A case-control study was conducted at the Nganda Hospital Center in Kinshasa, Democratic Republic of the Congo. One hundred and sixty patients with breast cancer (cases) were compared to 320 women who did not have BC (controls). STATA version 16 was used to analyze data with statistical significance considered at p < 0.05. Results: There is a strong association between BC in Congolese women and early menarche age (adjusted odds ratio [aOR] = 2.3; 95% CI: 1.2-4.3), family history of BC (aOR = 2.5; 95% CI: 1.2-5.5), overweight (aOR = 1.8; 95% CI: 1.1-2.7), and obesity (aOR = 7.3; 95% CI: 4.0-13.4). Conclusion: Our results indicate the presence of certain conventional risk factors. Thus, these results will be of great value in establishing adequate evidence-based awareness and preventive measures among the Congolese population.

Retrospection and prospect of Current Cancer Reports (CCR)

“…Zeng et al attempted the potentials of Pinus massoniana bark extract (PMBE), a Chinese natural product, on fighting against cancer via inducing the senescence of human hepatoma HepG2 cells in vitro [8]. Mukuku's team reported their series of research results on malignant tumors of Congo local characteristics [9][10][11][12]. Langer et al displayed their critical thinking about hematogone hyperplasia [13] and novel careful observation on Day 21 serum FLC level variation during therapy of symptomatic multiple myeloma [14].…”