2019
DOI: 10.1016/j.ijcard.2019.07.048
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Women with coronary microvascular dysfunction and no obstructive coronary artery disease have reduced exercise capacity

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Cited by 23 publications
(21 citation statements)
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References 40 publications
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“…47 Coronary microvascular dysfunction, present in some people recovering from COVID-19, 48 is also associated with chronotropic incompetence in the general population with microvascular dysfunction. 49,50 Autonomic Function in PASC Consistent with Ladlow et al's findings, altered autonomic function is the most likely unifying explanation for the constellation of findings observed in our study. 41 Alterations in autonomic function could explain chronotropic incompetence, blunted heart rate recovery, and reduction in heart rate variability.…”
Section: Findings Of Vascular Dysfunctionsupporting
confidence: 92%
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“…47 Coronary microvascular dysfunction, present in some people recovering from COVID-19, 48 is also associated with chronotropic incompetence in the general population with microvascular dysfunction. 49,50 Autonomic Function in PASC Consistent with Ladlow et al's findings, altered autonomic function is the most likely unifying explanation for the constellation of findings observed in our study. 41 Alterations in autonomic function could explain chronotropic incompetence, blunted heart rate recovery, and reduction in heart rate variability.…”
Section: Findings Of Vascular Dysfunctionsupporting
confidence: 92%
“…47 Coronary microvascular dysfunction, present in some people recovering from COVID-19, 48 is also associated with chronotropic incompetence in the general population with microvascular dysfunction. 49, 50…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Mean exercise capacity was lower than expected from sedentary, overweight women [30]. This has also been shown in a previous sub-study of women recruited from the iPOWER cohort [60]. Maximal workload improved in the intervention group and declined in the control group, but this improvement did not translate into an improvement in VO 2 peak, nor did it result in improved HR recovery or in ventilatory threshold as indicators of improved fitness and work economy, respectively.…”
Section: Exercise Capacitysupporting
confidence: 75%
“…Similarly, impaired coronary flow reserve is often detected in women with angina but no obstructive CAD using various invasive and non-invasive modalities ( 36 , 38 , 98 , 99 ), but flow reserve has not been found to be associated with angina burden in women ( 100 ). However, women with angina and CMD have reduced exercise capacity compared to asymptomatic women ( 101 ). The gap between angina and identifiable ischemia on stress testing has contributed to women without obstructive CAD being diagnosed with non-cardiac chest pain, and discharged from subspecialty care and treatment ( 102 ).…”
Section: Sex/gender In Chest Pain and Ischemic Heart Diseasementioning
confidence: 99%