Terminology represents a significant factor in healthcare communication between specialists and patients. The present paper deals with the lexicosemantic characteristics of multi-word lexical units multiple sclerosis, amyotrophic lateral sclerosis, Parkinson’s disease, Alzheimer’s disease, epidural abscess, Huntington’s chorea, and carpal tunnel syndrome. The research questions focus on collocations, word combinations, and concordances in which they regularly appear; the first lemma to the left and the first lemma to the right from the studied lexeme demonstrate the principal positions of our interest. Simultaneously, the researcher considers their semantic restrictions, semantic prosody, and grammatical relations that influence their lexical features. The whole linguistic material is investigated in the framework of the text corpus English Web 2015 (enTenTen15) with the help of the search tool Sketch Engine. To begin the research, the frequencies of these lexical units are elaborated. The researcher also looks into the morphological classification of the studied words as these two factors affect them from the lexicological perspective. The research outcomes confirm that the nervous disease names appear in a wide range of structures, and they considerably contribute to successful communication in the medical surroundings. Moreover, the results indicate that the lexicosemantic behaviour of the terms reflects extralinguistic factors (psychological, social) of individual communication acts. The phenomenon is to be further examined and interpreted within the corpus analyses of other chosen lexical units, not only from the field of medicine. Eventually, the researcher outlines possible pedagogical implications of the research results in the process of teaching English.