Background: Given the importance of the fit between workers' physical and mental abilities and their job needs, it is of great importance to assess, maintain and promote the work ability of the people. Objective: The current study, conducted in a petrochemicals company, aimed to assess the work ability of the personnel and its relationship with age and physical demands of work. Methods: The current cross sectional descriptive analytical study was conducted on 208 employees working in a petrochemical company. The authors studied different occupational groups including operators, administrative, laboratory, maintenance and warehouse personnel. The required data were collected from the target groups using self-report work ability index questionnaire. To analyze the data, SPSS software version 21 was used. The analysis was conducted using t-test, ANOVA and Pearson correlation coefficient.