Work capacity of the Czechoslovakian population

Seliger, V.; Mácek, M; Skranc, O; Horák, Jiří; Pirič, J.; Handzo, P; Rous, J; Jirka, Z

doi:10.1007/bf00421342

Cited by 11 publications

(12 citation statements)

References 16 publications

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“…Oxygen pulse [ V O2 /heart rate (HR)], respiratory exchange ratio between carbon dioxide production and oxygen consumption (RQ) and ventilatory equivalents for oxygen ( V E / V O2 ; V E = ventilation) and carbon dioxide ( V E / V CO2 ) were calculated. The main determinants of cardiorespiratory exercise capacity were referred to age‐ and body composition‐related reference values (Nordesjö & Landelius, 1975; Seliger et al. , 1978).…”

Section: Cardiorespiratory Measurementsmentioning

confidence: 99%

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Abnormal blood lactate accumulation after exercise in patients with multiple mitochondrial DNA deletions and minor muscular symptoms

Lindholm¹,

Löfberg²,

Somer³

et al. 2004

Clin Physio Funct Imaging

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Section: Cardiorespiratory Measurementsmentioning

confidence: 99%

“…The main determinants of cardiorespiratory exercise capacity were referred to age-and body composition-related reference values (Nordesjö & Landelius, 1975;Seliger et al, 1978). The main subjective limiting factors were asked.…”

Section: Cardiorespiratory Measurementsmentioning

confidence: 99%

Abnormal blood lactate accumulation after exercise in patients with multiple mitochondrial DNA deletions and minor muscular symptoms

Lindholm¹,

Löfberg²,

Somer³

et al. 2004

Clin Physio Funct Imaging

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“…The oxygen uptake over the last 30 seconds (V O 2 max, mL/min per kg) was recorded and calculated also as percentage of a value predicted by the patient's age and sex. 10 …”

Section: Exercise Testingmentioning

confidence: 99%

Mulibrey Heart Disease

et al. 2003

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Background— Mulibrey nanism is a rare inherited disease characterized by growth failure and multiorgan manifestations, including constrictive pericarditis. Its long-term course, the results of pericardiectomy, and the details of myocardial involvement have not been reported previously. Methods and Results— We studied 49 patients (26 men) born before 1985 and followed for up to 25 years. By 1999, 25 patients (51%) had developed congestive heart failure (CHF), 19 (39%) had undergone pericardiectomy for constrictive pericarditis, 10 (22%) had died of cardiac causes, and 5 (10%) had died of noncardiac causes. Of the 19 pericardiectomized patients, 12 derived lasting clinical benefit, whereas 1 patient suffered an early noncardiac death and 6 died later of unrelieved or recurrent CHF. At echocardiography in 34 living patients, left ventricular mass adjusted for body height and weight averaged (±SEM) 149±5 g in 21 unoperated patients, 144±8 g in 13 pericardiectomized patients, and 104±7 g in 16 healthy persons matched for age and sex ( P =0.000). Autopsies of 11 patients showed fibrotic thickening of the pericardial leaves with myocardial hypertrophy and variable but mostly mild myocardial fibrosis. Endocardial thickening was seen in 3 patients. Conclusions— Constrictive pericarditis, myocardial hypertrophy, and variable myocardial fibrosis constitute the main elements of Mulibrey heart disease. At least one half of patients ultimately develop CHF. Pericardiectomy generally provides clinical benefit, but in approximately one third of patients, CHF may recur because of coexisting myocardial involvement.

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“…Age-related changes in maximal exercise HR, and HR responsiveness, have been reported in the literature , Lester, Sheffield et al 1968, Kino, Lance et al 1975, Seliger, Macek et al 1978, Sheffield, Maloof et al 1978, Yin, Spurgeon et al 1979, Lalande, Sawicki et al 2014, and represent a sensitive indicator of autonomic dysfunction. Substantial research has shown that HRV decreases with age , Schwartz, Gibb et al 1991, Agelink, Malessa et al 2001, Bonnemeier, Richardt et al 2003, which has been observed in both cross-sectional comparisons and longitudinal studies (Sinnreich, Kark et al 1998).…”

Section: Effect Of Age On the Heartmentioning

confidence: 99%

“…However, although some inter-individual variation exists , advancing age impairs the magnitude of the HR and cardiac output responses at the exercise onset, resulting in a larger sympathetic drive to adjust blood pressure (Lalande, Sawicki et al 2014). The mechanism(s) affecting the diminished cardiac response with exercise in aging adults remains unknown but may include either changes in autonomic neural adjustments and/or intrinsic cardiac events , Lester, Sheffield et al 1968, Kino, Lance et al 1975, Seliger, Macek et al 1978, Sheffield, Maloof et al 1978, Yin, Spurgeon et al 1979, Craft and Schwartz 1995, Lalande, Sawicki et al 2014. Diminished HR variability (O'Brien, O'Hare et al 1986, Schwartz, Gibb et al 1991, Agelink, Malessa et al 2001, Bonnemeier, Richardt et al 2003) and a reduced tachycardia following atropine administration ) support the conclusion that age reduces chronic parasympathetic restraint of HR, suggesting that this effect may be a fundamental determinant of impaired cardiac acceleration with exercise in aging adults.…”

Section: Introductionmentioning

confidence: 99%