Work-Related and Occupational Liver Diseases

Abstract

D efinition of occupational diseases in the legislation; are the cases of temporary or permanent illness, physical or mental disability, which the insured suffers due to a recurring reason due to the nature of the work or the performance of the work. [1] Occupational diseases are diseases in which many causative factors and other risk factors play a role in the workplace. Etiology is complex. The causative agent of the disease does not have to be in the workplace. Occupational diseases are diseases in which many causative factors and other risk factors play a role in the workplace. Etiology is complex. Occupation causes, aggravates, accelerates or exacerbates illness and may reduce working capacity. Occupational diseases are more common than occupational diseases. Even if they do not arise directly from the workplace, they are affected by factors in the workplace. [2] The liver has many functions in the detoxification of toxins, alcohol and drugs in the blood, and in processing, synthesizing and storing various carbohydrates, lipids, proteins, vitamins and minerals. [3] Many factors such as alcohol addiction, various drugs, diets and systemic diseases such as heart failure, viral hepatitis, industrial chemicals such as occupational vinyl chloride, fungi containing hepatotoxins (amatoxin) (Amanita phalloides and Amanita verna) cause liver damage. [4] Occupational liver diseases may develop due to acute high dose and chronic low dose exposures in the workplace. While acute high-dose exposure is easy to define, the cause can be difficult to identify in low-dose chronic exposure. Epidemiological data in occupational liver diseases are insufficient. The limited awareness of hepatologists, the absence of pathognomonic findings for diagnosis, the absence of a sensitive biomarker, and the accompanying many other factors make it difficult to diagnose occupational liver disease. [5] According to the factor causing occupational disease; chemical causes, physical causes, biological causes and dusts. According to the factor causing occupational disease; chemical causes, physical causes, biological causes and dusts. In this article; The aim is to draw attention to occupational factors in liver diseases by classifying them according to factors and examining various reviews, research and case reports. It is to evaluate whether people with liver disease are exposed to these factors, to prevent exposure if there is, and to protect healthy workers in the same environment from this exposure.The liver is an organ responsible for the metabolism of drugs, many chemicals and various nutrients in the body. For this reason, it is inevitable that the liver will be affected by many factors that are exposed at work. Epidemiological data on occupational liver diseases are insufficient. It is always important to take an occupational anamnesis and evaluate the risks exposed while evaluating liver functions in periodic examinations at work, in hospital polyclinics.