SummaryAims. To identify and quantify the major sources of workplace and non-workplace stress, plus commonly used coping strategies among a group of cancer therapists. Method. Individual personal interviews were conducted with 16 radiation therapists (RTs) and 13 radiation oncology nurses (ONs) at two Brisbane hospitals. Results. Major workplace stressors were administration difficulties, patient issues, equipment and staffing issues. Major coping strategies included seeking help from mental health professionals, talking (with colleagues, supervisor, family), doing extra work, and doing nothing or withdrawing from work problems. Non-workplace stressors included family health and stress, relationship issues and financial problems. Coping strategies included taking time for self, exercise and acceptance. Discussion. Provision of psychotherapy services for cancer therapists requires accurate data regarding their major stressors and coping styles. The findings from this study help focus those services for maximum effectiveness.cancer / oncology / stress / nurses / radiation therapists Healthcare staff engage with patients across a range of illnesses and outcomes. Of those illnesses, perhaps none presents such potential for major disability and death as does cancer. It is therefore understandable that health professionals who work with cancer patients may experience occupational stress. This is because of the caring and empathic relationship between the two parties as well as the potentially negative outcomes of cancer on patient health and relationships. As evidence of that suggestion, prolonged stress and burnout have been reported in oncology nurses (ONs) [1,2,3] and radiation therapists (RTs) [4]. Counsellors who offer their services to these cancer-care professionals may therefore expect to encounter high levels of staff stress and burnout related to patient care issues. Alternatively, workplace stress can be caused by industrial/organisational issues, and the possible counselling interventions which might be relevant to those stressors experienced by cancercare staff will be different to those occasioned by patient death -and illness-related issues. In addition to patient care and organisational issues,