Working conditions and prevalence of pre‐eclampsia, Norway 1989

Wergeland, Ebba; Strand, Kitty

doi:10.1016/s0020-7292(97)00083-0

Cited by 47 publications

(49 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…(40) Second, the frequency and effect of other known risk factors (e.g., gravidity, number of fetuses, and maternal weight) are similar to those consistently reported in the literature, (41) and the associations with coffee intake and early menarche were also described in two previous publications. (42,43) Other previously suggested risk factors, such as advanced maternal age, diabetes, and Black race, were not associated with a higher frequency of gestational hypertension in our study; most likely because we excluded women with chronic hypertension (i.e., these factors were associated with hypertension diagnosed before 20 weeks of gestation). Our failure to find the previously suggested protective effect of smoking(44) might be due to differences among populations, methodological factors, or/and chance.…”

Section: Discussionmentioning

confidence: 66%

Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations

Hernández–Dı́az

Werler

Mitchell

2007

Fertility and Sterility

View full text Add to dashboard Cite

Objective-To investigate the association between infertility treatments and gestational hypertension and preeclampsia. Design-Retrospective observational cohort. Setting-General population, United States and Canada.Patients-5151 women with non-malformed infants participating in the Slone Epidemiology Center Birth Defects Study between 1998 and 2006.Interventions-Women were interviewed within six months after delivery about sociodemographic and medical factors, the onset of gestational hypertension and preeclampsia, and about infertility treatments.Main Outcome Measures-We estimated relative risks and 95% confidence intervals using unconditional logistic regression.Results-The incidence of gestational hypertension was 8.9% (423/4762) among women without infertility treatments, and 15.8% (55/349) among women undergoing infertility treatments. Compared to spontaneous pregnancies, the crude relative risk for gestational hypertension in pregnancies resulting from infertility treatments was 1.9 (95% confidence interval 1.4-2.6). Multivariate adjustment for parity and pre-pregnancy BMI resulted in a relative risk of 1.6 (1.1-2.1). Further adjustment for multiple pregnancies, or restriction of the analyses to singleton pregnancies, moved the relative risk to 1.3. Each specific infertility procedure or drug was associated with a similarly elevated risk, which disappeared after adjustment for multiple gestations. Results were similar for preeclampsia.Corresponding Author: Allen A. Mitchell, M.D., Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA, Tel: (617) 734 6006, Fax: (617) 738 5119, e-mail: E-mail: amitchell@slone.bu.edu. Conflict of interest: None CAPSULE:The higher incidence of gestational hypertension and preeclampsia in pregnancies resulting from infertility treatments is largely explained by the higher frequency of multiple gestations.Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Conclusion-Pregnancies resulting from infertility treatments have a higher incidence of gestational hypertension and preeclampsia than spontaneous conceptions. This increased risk is largely explained by the higher frequency of multiple gestations. NIH Public Access

show abstract

Section: Discussionmentioning

confidence: 66%

Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations

Hernández–Dı́az

Werler

Mitchell

2007

Fertility and Sterility

View full text Add to dashboard Cite

show abstract

“…One previous study showed a positive association between heavy lifting (10-20 kg or 22-44 lb) in early pregnancy (occurring more than 20 times per week) and preeclampsia. 24 Additionally, a 2-fold increased risk of preeclampsia was found for pregnant women with high physical activity at work (composite score). 7 An explanatory model by Paul et al 25 (1994) suggests that pregnancy-related musculoskeletal problems arise, at least in part, from reduced load-bearing capacity associated with joint laxity.…”

Section: Occupational Lifting and Fetal-maternal Health Outcomesmentioning

confidence: 99%

mentioning

confidence: 99%

Clinical guidelines for occupational lifting in pregnancy: evidence summary and provisional recommendations

MacDonald

Waters

Napolitano

et al. 2013

American Journal of Obstetrics and Gynecology

View full text Add to dashboard Cite

Empirically based lifting criteria established by the National Institute for Occupational Safety and Health (NIOSH) to reduce the risk of overexertion injuries in the general US working population were evaluated for application to pregnant workers. This report proposes criteria to guide decisions by medical providers about permissible weights for lifting tasks performed at work over the course of an uncomplicated pregnancy. Our evaluation included an extensive review of the literature linking occupational lifting to maternal and fetal health. Although it has been 29 years since the American Medical Association's Council on Scientific Affairs published its report on the Effects of Pregnancy on Work Performance, these guidelines continue to influence clinical decisions and workplace policies. Provisional clinical guidelines derived from the NIOSH lifting criteria that account for recent evidence for maternal and fetal health are presented and aim to improve the standard of care for pregnant workers. Keywordslifting; occupational hazard; pregnancy; recommendations Clinicians play an important role in decisions concerning work activity restrictions during pregnancy. This role is underscored in the United States where federal regulations for occupational lifting are lacking and limited opportunities for paid antenatal leave are available. 1,2 Findings from a recent survey show that recommendations to pregnant workers in physically demanding jobs vary widely, possibly because of limited clinician training in occupational health 3 and the absence of current authoritative guidelines. 4 The views expressed herein are those of the authors and do not necessarily represent the views of the National Institute for Occupational Safety and Health or the official policy or position of the Department of the Army, the Department of the Navy, the Department of Defense, or the United States Government.The authors report no conflict of interest.Reprints not available from the authors. HHS Public AccessAuthor manuscript Am J Obstet Gynecol. Author manuscript; available in PMC 2015 August 28. Author Manuscript Author Manuscript Author Manuscript Author ManuscriptTo address the need for updated empirically based recommendations that can be uniformly applied, this paper presents provisional clinical guidelines for occupational lifting in pregnancy based on an extensive review of the literature linking occupational lifting to maternal and fetal health and application of the National Institute for Occupational Safety and Health (NIOSH) lifting equation. Literature review criteriaAn extensive review of the literature linking occupational lifting to maternal and fetal health was conducted to inform the application of the NIOSH lifting equation to pregnant workers. Using the PubMed MESH Thesaurus terms, pregnancy, lifting, occupational diseases, preeclampsia, hypertension, pregnancy complications, pelvis, sacroiliac joint, pubic symphysis, range of motion articular, joint instability, relaxin, estradiol, biomechanics, stress mechanic...

show abstract

“…Recent reports, studying women working night shifts (in services such as healthcare, military, protection and airway), show associations between disrupting the light-dark cycle during pregnancy and a higher risk of PTB, low birth weight, spontaneous abortion and subfertility (Knutsson, 2003;Mahoney, 2010;Waddell et al, 2012). So far, however, only a few data are available on associations between alterations of the circadian rhythm and PE (Ditisheim et al, 2013;Haelterman et al, 2007;Mozurkewich et al, 2000;Wergeland & Strand, 1997). In this regard of interest is the hormone melatonin, which is regulated by the circadian clock and synthesized by the placenta thereby protecting against excessive oxidative stress involved in the pathogenesis of PE (Chen et al, 2013;Hobson et al, 2013;Valenzuela et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Early- and late-onset preeclampsia and the DNA methylation of circadian clock and clock-controlled genes in placental and newborn tissues

Berg

Chaves

Herzog

et al. 2017

Chronobiology International

View full text Add to dashboard Cite

The placenta is important in providing a healthy environment for the fetus and plays a central role in the pathophysiology of preeclampsia (PE). Fetal and placental developments are influenced by epigenetic programming. There is some evidence that PE is controlled to an altered circadian homeostasis. In a nested case-control study embedded in the Rotterdam Periconceptional Cohort, we obtained placental tissue, umbilical cord leukocytes (UCL), and human umbilical venous endothelial cells of 13 early-onset PE, 16 late-onset PE and 83 controls comprising 36 uncomplicated and 47 complicated pregnancies, i.e. 27 fetal growth restricted and 20 spontaneous preterm birth. To investigate the associations between PE and the epigenetics of circadian clock and clockcontrolled genes in placental and newborn tissues, genome-wide DNA methylation analysis was performed using the Illumina HumanMethylation450K BeadChip and a candidate-gene approach using ANCOVA was applied on 939 CpGs of 39 circadian clock and clock-controlled genes. DNA methylation significantly differed in early-onset PE compared with spontaneous preterm birth at 6 CpGs in placental tissue (3. ≤ p ≤ 0.009). No significant associations were shown with late-onset PE between study groups or tissues. The most differentially methylated CpGs showed hypomethylation in placental tissue and hypermethylation in uncomplicated controls. In conclusion, DNA methylation of circadian clock and clock-controlled genes demonstrated most differences in UCL of early-onset PE compared with spontaneous preterm birth. Implications of the tissue-specific variations in epigenetic programming for circadian performance and long-term health need further investigation.

show abstract

Working conditions and prevalence of pre‐eclampsia, Norway 1989

Abstract: Prenatal care should include assessment of working conditions, as early improvements may reduce the risk of pre-eclampsia.

Cited by 47 publications

References 14 publications

Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations

Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations

Clinical guidelines for occupational lifting in pregnancy: evidence summary and provisional recommendations

Early- and late-onset preeclampsia and the DNA methylation of circadian clock and clock-controlled genes in placental and newborn tissues

Contact Info

Product

Resources

About