ObjectiveTo compare the workplace experience of European and U.S. members of the otolaryngology community.MethodsEuropean and U.S. otolaryngologists‐head and neck surgeons (OTO‐HNS) were surveyed through three otorhinolaryngological societies. We inquired about personal and observed experiences of differential treatment in the workplace related to age, biological sex, ethnicity, disability, gender identity, political belief, and sexual orientation. Results were compared according to the world region. Differential treatment was used as a proxy for microaggressions.ResultsA total of 348 practitioners participated in the survey: 148 American and 230 European OTO‐HNS. European OTO‐HNS reported significantly higher proportions of observed or personal experiences of differential treatment based on age (p = .049), language proficiency (p = .027), citizenship (p = .001), hair texture (p = .017), height/weight (p = .002), clothing (p = .011), and professionalism (p = .002) compared with U.S. OTO‐HNS. Differential treatment related to political belief (p = .043), socioeconomic status (p = .018), and ethnicity (p = .001) were higher in the United States compared with Europe. Feelings of exclusion (p = .027) and consideration of leaving their position (p = .001) were significantly higher in the United States compared with Europe. In both the United States and Europe, female OTO‐HNS reported more frequent differential treatment related to biological sex than males.ConclusionDifferential treatment, or microaggressions, related to personal characteristics or behavior varied in the United States and Europe with more ethnicity‐based microaggressions in the United States and physical characteristic‐based microaggressions in Europe. In both regions, females were more subject to microaggressions than males. More efforts are needed to tackle microaggressions and discrimination in the clinical and academic workplace of the Western otolaryngology community.Level of Evidence4.