World Federation for Ultrasound in Medicine Review Paper: Incidental Findings during Obstetrical Ultrasound

Petousis, Stamatios; Chatzakis, Christos; Westerway, Susan Campbell; Abramowicz, Jacques S.; Dinas, Konstantinos; Dong, Yi; Dietrich, Christoph F.; Sotiriadis, Alexandros

doi:10.1016/j.ultrasmedbio.2021.09.010

Cited by 7 publications

(6 citation statements)

References 60 publications

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“…IFs on imaging studies are asymptomatic and unexpected pathologies, unrelated to the presenting illness. They often necessitate further imaging or diagnostic work-ups which entail both a psychological and an economic burden for the patient and the healthcare system [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ].…”

Section: Definitionmentioning

confidence: 99%

“…The following issues are almost identical for the evaluation of IF in all organs and will be briefly summarized [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 219 ].…”

Section: What Is the Impact Of An Incidental Finding In Pediatric Ult...mentioning

confidence: 99%

“…The World Federation for Ultrasound in Medicine and Biology (WFUMB) is addressing the issue of incidental findings (IFs) with a series of publications titled “Incidental imaging findings—the role of ultrasound” [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. Each WFUMB position paper on IFs will follow the same template and, accordingly, will be uniformly structured to help readers interpret the key messages [ 7 ], will discuss the prevalence and imaging features of hepatic incidental finding in pediatric patients and will discuss strategies for work- and follow-up.…”

Section: Introduction and Definitionmentioning

confidence: 99%

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Incidental Findings in Pediatric Patients: How to Manage Liver Incidentaloma in Pediatric Patients

Čekuolis

Schreiber-Dietrich

Augustinienė

et al. 2023

Cancers

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The World Federation for Ultrasound in Medicine and Biology (WFUMB) is addressing the issue of incidental findings (IFs) with a series of publications entitled “Incidental imaging findings—the role of ultrasound”. IFs in the liver of newborns and children are rare and much less commonly encountered than in adults; as a result, they are relatively much more frequently malignant and life-threatening, even when they are of benign histology. Conventional B-mode ultrasound is the well-established first line imaging modality for the assessment of liver pathology in pediatric patients. US technological advances, resulting in image quality improvement, contrast-enhanced ultrasound (CEUS), liver elastography and quantification tools for steatosis have expanded the use of ultrasound technology in daily practice. The following overview is intended to illustrate incidentally detected liver pathology covering all pediatric ages. It aims to aid the examiner in establishing the final diagnosis. Management of incidentally detected focal liver lesions (FLL) needs to take into account the diagnostic accuracy of each imaging modality, the patient’s safety issues (including ionizing radiation and nephrotoxic contrast agents), the delay in diagnosis, the psychological burden on the patient and the cost for the healthcare system. Moreover, this paper should help the pediatric clinician and ultrasound practitioner to decide which pathologies need no further investigation, which ones require interval imaging and which cases require further and immediate diagnostic procedures.

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Section: Definitionmentioning

confidence: 99%

“…The following issues are almost identical for the evaluation of IF in all organs and will be briefly summarized [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 219 ].…”

Section: What Is the Impact Of An Incidental Finding In Pediatric Ult...mentioning

confidence: 99%

Section: Introduction and Definitionmentioning

confidence: 99%

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Incidental Findings in Pediatric Patients: How to Manage Liver Incidentaloma in Pediatric Patients

Čekuolis

Schreiber-Dietrich

Augustinienė

et al. 2023

Cancers

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“…Adnexal masses during pregnancy are not common and are often incidentally found at the time of routine ultrasound [57]. The majority of adnexal masses are benign, but pose a risk for adnexal torsion [58].…”

Section: Special Population: Pregnant Patientsmentioning

confidence: 99%

Adnexal torsion: a review of diagnosis and management strategies

Chang-Patel

Palacios-Helgeson

Gould

2022

Current Opinion in Obstetrics &Amp; Gynecology

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Purpose of reviewAdnexal torsion remains a diagnostic challenge heavily reliant on high clinical suspicion, with patient presentation and imaging used as adjuncts to aid in its diagnosis. This review summarizes diagnostic and management techniques of adnexal torsion to assist providers when encountering this surgical emergency. Recent findingsCommon findings of adnexal torsion include abdominal pain, nausea, vomiting, and adnexal mass or ovarian enlargement. An elevated neutrophil to lymphocyte ratio may be useful for diagnosis. A 'whirlpool' sign, 'follicular ring' sign, enlarged/edematous ovary, and absent Doppler flow to the ovary are highly suggestive of adnexal torsion. Intraoperative visual diagnosis of ovarian death is highly inaccurate, with only 18--20% of ovaries necrotic on pathological examination. Necrotic appearing ovaries have been shown to have follicular activity on ultrasound one year postoperatively.

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“… 4 While imaging can be used to detect ovarian masses, it cannot make a definitive diagnosis or differentiate benign from malignant lesions, and the lesion cannot be detected until the size reaches a significant level. 5 There remains a deficiency in specificity concerning tumor marker testing alone, transvaginal ultrasound screening alone, or their combined use, which results in unsatisfactory rates of early detection. Multigene testing is useful for identifying individuals with OC at high risk, predicting their prognosis, and selecting therapeutic agents.…”

Section: Introductionmentioning

confidence: 99%

Ovarian Cancer Diagnosis and Prognosis Based on Cell-Free DNA Methylation

Gao,

Zhou,

Liu

2024

Cancer Control

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Background: Ovarian cancer stands as the deadliest malignant tumor within the female reproductive tract. As a result of the absence of effective diagnostic and monitoring markers, 75% of ovarian cancer cases are diagnosed at a late stage, leading to a mere 50% survival rate within five years. The advancement of molecular biology is essential for accurate diagnosis and treatment of ovarian cancer. Methods: A review of several randomized clinical trials, focusing on the ovarian cancer, was undertaken. The advancement of molecular biology and diagnostic methods related to accurate diagnosis and treatment of ovarian cancer were examined. Results: Liquid biopsy is an innovative method of detecting malignant tumors that has gained increasing attention over the past few years. Cell-free DNA assay-based liquid biopsies show potential in delineating tumor status heterogeneity and tracking tumor recurrence. DNA methylation influences a multitude of biological functions and diseases, especially during the initial phases of cancer. The cell-free DNA methylation profiling system has emerged as a sensitive and non-invasive technique for identifying and detecting the biological origins of cancer. It holds promise as a biomarker, enabling early screening, recurrence monitoring, and prognostic evaluation of cancer. Conclusions: This review evaluates recent advancements and challenges associated with cell-free DNA methylation analysis for the diagnosis, prognosis monitoring, and assessment of therapeutic responses in the management of ovarian cancers, aiming to offer guidance for precise diagnosis and treatment of this disease.

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World Federation for Ultrasound in Medicine Review Paper: Incidental Findings during Obstetrical Ultrasound

Cited by 7 publications

References 60 publications

Incidental Findings in Pediatric Patients: How to Manage Liver Incidentaloma in Pediatric Patients

Incidental Findings in Pediatric Patients: How to Manage Liver Incidentaloma in Pediatric Patients

Adnexal torsion: a review of diagnosis and management strategies

Ovarian Cancer Diagnosis and Prognosis Based on Cell-Free DNA Methylation

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