This is a systematic review of the literature on the Belt and Road Initiative (BRI) and its impact on tourism and heritage in participating countries along the Silk Roads. China launched the BRI in 2013 with the aim of promoting global trade and stimulating economic growth through the development of infrastructure and cultural cooperation. This review examines studies for the period from 2013 to 2023, focusing on key themes such as tourist flows, destination development, urban renewal, heritage preservation, and cultural route revival. The systematic review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, incorporating 56 relevant documents that cover both tourism and heritage domains. The findings highlight substantial potential for the development of new tourism products and destinations, improved urban renewal, and the preservation of cultural heritage, provided that integrated policies, public-private collaboration, and equitable community participation frameworks are implemented with attention to ecological limits. However, the review also identifies significant challenges, including financial imbalances, uneven access to benefits, social disruption, cultural commodification, and environmental degradation. Addressing these issues requires careful, context-specific planning. The study concludes with a proposal for a future research agenda that includes exploring underrepresented regions, developing sustainable tourism models, and fostering interdisciplinary research to ensure a balanced approach to economic development and heritage preservation. This review’s findings provide valuable insight for policymakers, tourism officials, and cultural heritage managers, guiding the development of policies that balance economic growth with the preservation of cultural and natural heritage sites. This research contributes to the academic discourse by elucidating the complex interplay between the BRI and the Silk Roads’ tourism and heritage, offering a pathway for sustainable and inclusive growth.