The COVID-19 pandemic has underscored the risk that animal diseases pose to human health. A 2012 study estimated that some 56 zoonoses (i.e. diseases affecting human health that originate in animals) were together responsible for around 2.5 billion cases of human illness and 2.7 million human deaths a year. The impact of COVID-19 has far eclipsed that of other recent outbreaks of such diseases. Experts warn that zoonotic pandemics may become more frequent due to factors including further environmental degradation, intensive farming practices, and the effects of climate change.WTO rules recognize the right of WTO members to take measures to protect human, animal and plant health. The Agreement on the Application of Sanitary and Phytosanitary Measures (SPS Agreement) underscores their right to take measures to address the health risks arising from the spread of zoonoses through international trade in animals and animal products, including wildlife, while aiming to avoid unjustified trade barriers.The SPS Agreement strongly encourages WTO members to base their SPS measures on certain international standards. In the area of animal health and zoonoses, it recognizes the standards developed by the World Organisation for Animal Health (OIE).According to both the World Health Organization (WHO) and the OIE, the COVID-19 pandemic is being sustained through human-to-human transmission and not through international trade in animals and animal products. Based on currently available information, and with the support of expert advisory groups, the OIE does not recommend that any COVID-19-related sanitary measures be applied to the international movement of live animals or animal products without a justifying risk analysis. Trade in animals and animal products can take place safely if risk reduction measures are applied based on international standards.Risks associated with trade in animals and animal products, including wildlife, may increase when animal disease risks are not monitored and controlled. The OIE Working Group on Wildlife and other international organizations are examining how better to address sanitary risks linked to wildlife trade. Efforts are also being made to address illegal wildlife trade.Around 20 per cent of livestock production is lost due to animal diseases every year -leading to an estimated annual economic loss within the sector of about US$ 300 billion. The impact of COVID-19, which primarily affects people, has already dwarfed these figures. Global economic output is projected to shrink by 4.5 per cent in 2020 because of the pandemic, according to estimates by the IMF. As of 6 October 2020, WTO economists expect global trade to contract by 9.2 per cent in 2020.