Worldwide burden of antidiabetic drug-induced sarcopenia: An international pharmacovigilance study

Kong, Jaehyun; Park, Seoyoung; Kim, Tae Hyeon; Lee, Jae E.; Cho, Hanseul; Oh, Jiyeon; Lee, Sooji; Jo, Hyesu; Lee, Hayeon; Lee, Kyeongmin; Park, Jaeyu; Jacob, Louis; Pizzol, Damiano; Rhee, Sang Youl; Kim, Sunyoung; Yon, Dong Keon

doi:10.1016/j.archger.2024.105656

Archives of Gerontology and Geriatrics

2025

DOI: 10.1016/j.archger.2024.105656

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Worldwide burden of antidiabetic drug-induced sarcopenia: An international pharmacovigilance study

Jaehyun Kong,

Seoyoung Park,

Tae Hyeon Kim

et al.

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Type 2 diabetes: a contemporary view from the Asian lens

Ratnasingam,

Lim,

Chan

2024

Current Opinion in Endocrinology, Diabetes &Amp; Obesity

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Purpose of review The aim of this article was to review the up-to-date evidence with regards to the unique features of the Type 2 diabetes (T2D) pathophysiology, complications, response to therapy with the possibility of precision medicine guiding therapeutic decision making in Asia. Recent findings Asia is the epicenter of diabetes. There have been marked advances with genotyping and phenotyping of the Asian patient with T2D, particularly with young onset diabetes where early beta cell failure and rapid progression of complications are more frequent. As Asians have lower muscle mass and higher adiposity, sarcopenia is increasingly associated with diabetes. Response to lifestyle and pharmacotherapy are generally similar, but unique features exist with different populations. Across Asia, use of guideline directed medical therapy for cardio-renal protection are recommended, but uptake of these newer agents are suboptimal and barriers exist with regards to standardized care. Summary Although many similarities have been observed across Asia, due to the heterogeneity of populations within Asia, further research is required to streamline and pave the way towards precision medicine. There is an urgent need for region wide consensus to minimize barriers to diabetes care and stigma in diabetes terminology across Asia.

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Type 2 diabetes: a contemporary view from the Asian lens

Ratnasingam,

Lim,

Chan

2024

Current Opinion in Endocrinology, Diabetes &Amp; Obesity

View full text Add to dashboard Cite

show abstract

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Worldwide burden of antidiabetic drug-induced sarcopenia: An international pharmacovigilance study

Cited by 1 publication

References 44 publications

Type 2 diabetes: a contemporary view from the Asian lens

Type 2 diabetes: a contemporary view from the Asian lens

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