Worldwide differences of hospitalization for ST-segment elevation myocardial infarction during COVID-19: A systematic review and meta-analysis

Sofi, Francesco; Dinu, Monica; Reboldi, Gian Paolo; Stracci, Fabrizio; Pedretti, Roberto F.E.; Valente, Serafina; Gensini, Gian Franco; Gibson, C. Michael; Ambrosio, Giuseppe

doi:10.1016/j.ijcard.2021.10.156

Cited by 48 publications

(51 citation statements)

References 45 publications

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“…Further work is needed to determine what factors contributed most to the decreased and delayed AMI presentation and increased mortality. In particular, a recent study reviewed all available information on the incidence of STEMI hospitalizations during the COVID-19 pandemic, worldwide, focusing on the possible factors underlying discrepant results ( 48 ). This study confirmed that during the first peak of the COVID-19 pandemic, there has been a significant decrease in STEMI hospitalizations worldwide.…”

Section: Clinical Characteristics and Outcomes Of Patients With Ami During Covid-19mentioning

confidence: 99%

“…However, the magnitude of decrease was of a lesser extent than initially described. Most importantly, through a meta-analytical approach of a significant number of reports that includes >100,000 cases from 57 countries, and systematic assessment of various health-related metrics, substantial differences emerged among studies and countries, probably due to different functioning of hospital services and different hub-and-spoke approaches to STEMI, along with adequate public information during the pandemic ( 48 ). As different phases of the COVID-19 pandemic took shape, other investigations have been published to update the epidemiological picture of AMI, both at a national and at a global level.…”

Section: Clinical Characteristics and Outcomes Of Patients With Ami During Covid-19mentioning

confidence: 99%

See 1 more Smart Citation

Acute Myocardial Infarction During the COVID-19 Pandemic: An Update on Clinical Characteristics and Outcomes

Toscano

Cosentino

Campodonico

et al. 2021

Front. Cardiovasc. Med.

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The outbreak of coronavirus disease 2019 (COVID-19) has rapidly become a worldwide pandemic. On top of respiratory complications, COVID-19 is associated with major direct and indirect cardiovascular consequences, with the latter probably being even more relevant, especially in the setting of time-dependent cardiovascular emergencies. A growing amount of data suggests a dramatic decline in hospital admissions for acute myocardial infarction (AMI) worldwide during the COVID-19 pandemic, mostly since patients did not activate emergency medical systems because hospitals were perceived as dangerous places regarding the infection risk. Moreover, during the COVID-19 pandemic, patients with AMI had a significantly higher in-hospital mortality compared to those admitted before COVID-19, potentially due to late arrival to the hospital. Finally, no consensus has been reached regarding the most adequate healthcare management pathway for AMI and shared guidance on how to handle patients with AMI during the pandemic is still needed. In this review, we will provide an update on epidemiology, clinical characteristics, and outcomes of patients with AMI during the COVID-19 pandemic, with a special focus on its collateral cardiac impact.

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Section: Clinical Characteristics and Outcomes Of Patients With Ami During Covid-19mentioning

confidence: 99%

Section: Clinical Characteristics and Outcomes Of Patients With Ami During Covid-19mentioning

confidence: 99%

Acute Myocardial Infarction During the COVID-19 Pandemic: An Update on Clinical Characteristics and Outcomes

Toscano

Cosentino

Campodonico

et al. 2021

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

show abstract

“…Besides, due to the limited resources, there was the necessity to preserve PPE, cardiopulmonary assistance equipment and ICU beds occupation, as well as to rearrange lots of services of healthcare system in general. As a result, access to cardiovascular assistance was limited in the whole Italian territory and relevant issues regarding the priority of cardiac cares and invasive treatments, emerged [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Transcatheter aortic valve implantation during COVID-19 pandemic: An optimized model to relieve healthcare system overload

Reddavid

Costa

Valvo

et al. 2022

International Journal of Cardiology

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Background The coronavirus 2019 (COVID-19) pandemic upset healthcare systems and their logistics worldwide. We sought to assess safety and effectiveness of an optimized logistics for transcatheter aortic valve implantation (TAVI) pathway developed during the COVID-19 pandemic. Methods This is a retrospective analysis. An optimized TAVI logistics based on performing TAVI work-up and procedure during the same hospitalization was used during the COVID-19 pandemic. In-hospital and 30-day outcomes of patients treated during the pandemic were compared with an historical cohort of patients undergoing TAVI with staged work-up before the pandemic within an homogeneous timeframe. Results Of 536 patients, 227 (42.4%) underwent TAVI during the COVID-19 pandemic with a reduction of 26.5% compared to the pre-pandemic period ( n = 309). The median age was 81 (77–85) years and STS score was 3.4 (2.2–5.6)%. Lower rates of in-hospital major vascular complications (2.2% vs. 8.7%; p < 0.01) and life-threatening bleeding (0.4% vs. 4.2%; p = 0.01) were reported in the COVID-19 period, whereas no difference in acute kidney injury (7.0% vs. 7.4%, p = 0.85) rate was reported between COVID-19 and pre-COVID-19 periods. No difference in 30-day rates of all-cause death (4.0 vs. 4.5, p = 0.75) and of major adverse cardiovascular events (4.0 vs. 6.1, p = 0.26) were reported between COVID-19 and pre-COVID-19 periods. Conclusions The use of optimized single-hospitalization logistics for TAVI workup and procedure developed during the COVID-19 pandemic, showed to be as safe and effective as the two-stage TAVI pathway previously adopted, allowing the minimization of potential exposure to COVID-19 infection and shortening times to treatment for severely symptomatic patients.

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“…Thus, in this issue of the Journal Sofi and colleagues assessed how the SARS-CoV2 pandemic affected medical care of STEMI patients in a systematic review [ 3 ]. In a worldwide comparison of hospitalization of more than 111.000 STEMI patients, Sofi et al impressively showed that there had been a 20% decrease in inpatient admissions and care of these patients.…”

mentioning

confidence: 99%

“…Another important aspect addressed by Sofi and colleagues is the painstaking review of the included studies in terms of methodology and quality [ 3 ]. This is noteworthy because the efforts of scientists worldwide to cope with the SARS-CoV2 pandemic have resulted in a flood of publications on this topic.…”

mentioning

confidence: 99%

Factors influencing medical care of STEMI patients during the COVID-19 pandemic worldwide

Ong

Allgäuer

2022

International Journal of Cardiology

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Worldwide differences of hospitalization for ST-segment elevation myocardial infarction during COVID-19: A systematic review and meta-analysis

Cited by 48 publications

References 45 publications

Acute Myocardial Infarction During the COVID-19 Pandemic: An Update on Clinical Characteristics and Outcomes

Acute Myocardial Infarction During the COVID-19 Pandemic: An Update on Clinical Characteristics and Outcomes

Transcatheter aortic valve implantation during COVID-19 pandemic: An optimized model to relieve healthcare system overload

Factors influencing medical care of STEMI patients during the COVID-19 pandemic worldwide

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