2010
DOI: 10.1097/mbc.0b013e328339cc33
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Worm-like thrombus in left main coronary artery after cytostatic treatment

Abstract: This paper reports a 43-year-old patient who had a large, mobile, worm-like thrombus in the left main coronary artery after receiving a chemotherapy regimen containing cisplatin, bleomycin and etoposide for a nonseminomatous testes tumor. The patient was successfully treated with thrombolytic therapy. Physicians should be aware that thrombotic events may be observed after the administration of certain chemotherapeutic agents, particularly cisplatin.

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Cited by 3 publications
(3 citation statements)
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“…Although we commonly expect venous thrombosis in the setting of malignancies, an arterial thrombosis revealed the first manifestation of hypercoagulable state of the underlying cancer [3]. Management of left main thrombosis is often controversial including conservative approach with antiplatelet drugs, mechanical aspiration thrombectomy, stenting, intracoronary or systemic thrombolytic delivery or urgent CABG [1,2,8]. This case underscores the importance of malignancies that may lead to a catastrophic STEMI due to a hypercoagulable state and following thrombosis in the left main coronary artery.…”
Section: Discussionmentioning
confidence: 99%
“…Although we commonly expect venous thrombosis in the setting of malignancies, an arterial thrombosis revealed the first manifestation of hypercoagulable state of the underlying cancer [3]. Management of left main thrombosis is often controversial including conservative approach with antiplatelet drugs, mechanical aspiration thrombectomy, stenting, intracoronary or systemic thrombolytic delivery or urgent CABG [1,2,8]. This case underscores the importance of malignancies that may lead to a catastrophic STEMI due to a hypercoagulable state and following thrombosis in the left main coronary artery.…”
Section: Discussionmentioning
confidence: 99%
“…Occlusion of the left main coronary artery (LMCA) with thrombus is rare but it's very mortal case. 1,2 Choice of treatment options depend on the clinical presentation of the patient and result of angiographic examination. Total occlusion of the LMCA with thrombus can be treated with percutaneus coronary intervention under intraaortic balon pump back up.…”
Section: Akut Miyokard Infaktüsüne Neden Olan Sol Ana Koroner Arter I...mentioning
confidence: 99%
“…3 Subtotal thrombotic occlusion of the LMCA can be successfully treated with coronary artery bypass graft (CABG) operation or thrombolytic treatment. [1][2] We present a 54-year old man referred to our hospital with acute anterior myocardial infarction. The coronary angiogram performed with guiding…”
Section: Akut Miyokard Infaktüsüne Neden Olan Sol Ana Koroner Arter I...mentioning
confidence: 99%