Worsening Lower Jaw Swelling and Pain in a Teenager: Differential Diagnosis and Management

Kahlon, Gurleen Kaur; Tilak, Kedar; Kondamudi, Noah P.

doi:10.7759/cureus.18296

Cited by 2 publications

(3 citation statements)

References 19 publications

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“…4 ). 11 12 13 14 The same radiographic features have also been reported in other giant cell lesions such as giant cell tumors and brown tumors of hyperparathyroidism. 14 In a systematic review, Stavropoulos and Katz 11 showed that 53% of all central giant cell granulomas had scalloped margins.…”

Section: Resultssupporting

confidence: 66%

“… 11 12 13 14 The same radiographic features have also been reported in other giant cell lesions such as giant cell tumors and brown tumors of hyperparathyroidism. 14 In a systematic review, Stavropoulos and Katz 11 showed that 53% of all central giant cell granulomas had scalloped margins. The presence of scalloped margins in this entity has also been reported by Kahlon et al 14 In addition, they also pointed out that this radiographic feature can be seen in giant cell granulomas associated with genetic disorders such as Noonan syndrome, neurofibromatosis, cherubism, and arteriovenous malformations.…”

Section: Resultssupporting

confidence: 66%

“… 14 In a systematic review, Stavropoulos and Katz 11 showed that 53% of all central giant cell granulomas had scalloped margins. The presence of scalloped margins in this entity has also been reported by Kahlon et al 14 In addition, they also pointed out that this radiographic feature can be seen in giant cell granulomas associated with genetic disorders such as Noonan syndrome, neurofibromatosis, cherubism, and arteriovenous malformations. 14 The same findings were also reported by Vaidya et al 15 and Jeyaraj.…”

Section: Resultsmentioning

confidence: 99%

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Scalloped border as a possible diagnostic aid for differentiating jaw lesions: A pictorial essay

2022

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Purpose The aim of this study was to introduce a category of jaw lesions comprising cysts and tumors associated with scalloped borders. Materials and Methods General search engines and specialized databases including Google Scholar, PubMed, PubMed Central, and Scopus, as well as an authoritative textbook, were used to find relevant studies by using keywords such as “jaw lesion,” “jaw disease,” “scalloping,” “scalloped border,” “scalloped margin,” “irregular border,” and “irregular margin.” Out of 289 articles, 252 records were removed because they were duplicates, did not have a relevant title, or did not mention the frequency of findings described using the term “scalloped border.” Finally, 37 closely related articles were chosen. Results According to the relevant literature, scalloped borders are found most frequently in ameloblastoma, followed by simple bone cyst, central giant cell granuloma, odontogenic keratocyst, and glandular odontogenic cyst. Conclusion The lesions most frequently reported to have scalloped borders are ameloblastoma, central giant cell granuloma, odontogenic keratocyst, simple bone cyst, and glandular odontogenic cyst.

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Section: Resultssupporting

confidence: 66%

Section: Resultssupporting

confidence: 66%

Section: Resultsmentioning

confidence: 99%

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Scalloped border as a possible diagnostic aid for differentiating jaw lesions: A pictorial essay

2022

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Evaluating Treatment Modalities for Reducing Recurrence in Central Giant Cell Granuloma: A Narrative Review

Aliu,

Shabani,

Aliu

et al. 2024

Dentistry Journal

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Treating central giant cell granuloma (CGCG) is challenging due to high recurrence rates and variable therapy responses. This study examines the efficacy of various treatments in reducing CGCG recurrence. A literature review explored outcomes of surgical excision, curettage, intralesional corticosteroid injection, and adjuvant therapy, considering factors like lesion location, size, and histological features. Aggressive surgical techniques such as en bloc resection were found to potentially lower recurrence rates compared to conservative approaches. However, treatment should be tailored to individual patient needs. Further research is needed to confirm these findings and improve treatment strategies. A concise literature review was conducted using PubMed, MEDLINE, and Google Scholar, focusing on papers published from 1986 to 2024. Search terms included “central giant cell granuloma”, “recurrence”, “treatment modalities”, and “surgical excision”. Studies reporting recurrence rates and treatment outcomes for CGCG were analyzed. Twenty-nine studies were reviewed, including six studies on surgical excision and curettage, eight studies on intralesional corticosteroid injections, six studies on calcitonin therapy, five studies on interferon-alpha therapy, and four studies on the therapy with denosumab. Analysis indicated that aggressive surgical treatments like en bloc resection were associated with lower recurrence rates compared to conservative methods. Predictors of recurrence included lesion size (>3 cm), location (mandible), and aggressive histopathological features. Aggressive surgical excision combined with nonsurgical methods may lower recurrence rates, while conservative techniques remain viable in some cases. Further prospective research is needed to validate these findings and enhance CGCG treatment options.

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Worsening Lower Jaw Swelling and Pain in a Teenager: Differential Diagnosis and Management

Cited by 2 publications

References 19 publications

Scalloped border as a possible diagnostic aid for differentiating jaw lesions: A pictorial essay

Scalloped border as a possible diagnostic aid for differentiating jaw lesions: A pictorial essay

Evaluating Treatment Modalities for Reducing Recurrence in Central Giant Cell Granuloma: A Narrative Review

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