Wound care in the dermatology office: Where are we in 2011?

Rosso, J.Q. Del

doi:10.1016/j.jaad.2010.10.038

Cited by 24 publications

(21 citation statements)

References 54 publications

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“…erythromycin [53] and one for local use, fusidic acid. Spontaneous clearing of the infections without antimicrobial treatment was an encouraging observation, as there was no approved drug available in the studied cases and antimicrobial resistance is expanding and antimicrobials are considered a limited resource [54,55]. Wound care without antimicrobial treatment is a topic that needs to be further explored within veterinary practices, as well as in research.…”

Section: Discussionmentioning

confidence: 99%

The first nosocomial outbreak of methicillin-resistant Staphylococcus aureus in horses in Sweden

Bergström

Aspán²,

Landén³

et al. 2012

Acta Vet Scand

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BackgroundMethicillin-resistant Staphylococcus aureus (MRSA) in animals is a rare finding in Sweden. In horses, MRSA was first detected in a screening survey in 2007. In 2008, six clinical cases occurred in an equine hospital, indicating an outbreak.MethodAll MRSA isolates detected, 11 spa-type t011 and one t064 (n = 12), in infected horses (n = 10) and screening of horses (n = 2) in Sweden from December 2007 to March 2010 were retrospectively analysed with pulsed-field gel electrophoresis (PFGE) using Cfr9I and ApaI restriction enzymes, to study relationship between the isolates. Medical records of infected horses and outbreak investigation notes were scrutinised to monitor the clinical outcome and other aspects of the outbreak.ResultsEight of the 10 infected horses were linked to one equine hospital and two to another hospital in the same region. The six horses infected with MRSA in 2008 underwent surgery during the period 22 May-7 July in one of the hospitals. Four more infections linked to the two hospitals were notified between 2009 and March 2010.Nine of the 11 spa-type t011 isolates had identical Cfr9I and ApaI PFGE pattern. All six infected horses from 2008 presented with this MRSA. Two t011 isolates differed in one and two bands, respectively, in PFGE.Nine horses suffered from surgical site infections (SSI). No antimicrobials were used following the MRSA diagnosis and the infections cleared. The time from surgery to MRSA diagnosis differed greatly between the horses (range 15-52 days).ConclusionsAssociation in time and space of six horses infected with an identical MRSA strain of spa-type t011 confirmed an outbreak. Two isolates found in 2009 and 2010 in the outbreak hospital were closely related to the outbreak strain, indicating one circulating strain. Both spa-type t011 and t064 have been reported in horses in Europe prior to these findings. The observation that the infections cleared although antimicrobials were not used is encouraging for future prudent use of antimicrobials. The time from surgery to bacteriological diagnosis was not acceptable in most cases, as contagious spread was a risk. Sampling when symptoms of infection are noticed and accurate analysis are thus important.

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Section: Discussionmentioning

confidence: 99%

The first nosocomial outbreak of methicillin-resistant Staphylococcus aureus in horses in Sweden

Bergström

Aspán²,

Landén³

et al. 2012

Acta Vet Scand

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“…15,17 Biopsy sites should be dressed with a moist occlusive dressing and paraffin ointment that should remain undisturbed for 24 to 48 hours. 10,15,17,18,19 Thereafter, until re-epithelialisation is complete, wounds should be gently cleaned daily with warm water and reapplication of paraffin ointment with nonstick dressing. 10,15,18,19 Topical antibiotics are no more effective than white soft paraffin.…”

Section: Postoperative Carementioning

confidence: 99%

Improving diagnostic accuracy of skin biopsies

Stevenson¹,

Rodins²

2018

Aust J Gen Pract

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“…Wound infection is the body tissue damage caused by various injury factors， which is a common dynamic process that begins from the moment of injury , lack of specificity and useful treatment [1][2] .when the body is suffered wound infection , a series of complex cell biology effects has been started in one's body , including activation and transfer of stress signals, imbalance of inflammations, release of various harmful factors and etc.inflammatory cytokines are sensitive indicators of post-traumatic inflammation, which includes TNFA,IL-1,IL-6,C-reactive protein and etc [3][4][5] .By monitoring of these important indicators, we can evaluate the severity of the inflammation, and know the development of inflammatory.By far, the most common treatment for wound infection is surgical debridement, which can eliminate the inflammation rigorously but has avoidless cut, and has high recurrence rate [6].…”

Section: Introductionmentioning

confidence: 99%

In Vivo Assessments of Minocycline combined Hyaluronic Acid-mediated Ultrasound Therapy of Infected Wound in Rats

Zhang

Zhuang

2018

Preprint

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Objectives: The purpose of our research was to examine the effects of Minocycline combined hyaluronic acid (HA)-mediated Ultrasound therapy of infected wound in wister rats .Methods: 40 female wister rats were made wound on the two side of the backbone, then infected in Staphylococcus aureus at the comic for three times. then ,they are divided into four groups: control group, minocycline combined HA alone, ultasound alone , minocycline combined HA-mediated ultasound group ,respective. After 3 times of treatments, the rats were killed and made into specimens.Assessments consisted of visual inspection in the change of the skin, scar formation pathological morphology by hematoxylin and eosin(HE) stain with optical microscopy,IL-1B assaying and TNF-a were performed. Result: Compared with control group, minocycline combined HA alone, ultasound alone, minocycline combined HA-mediated ultasound group all have effect for wound healing, there was a obvious improvement in all parameters over the duration of the experiment(P<0.05). Compared with the control group, minocycline combined HA-mediated ultasound group indicated less inflammation cells (P<0.001) and the reduce of and IL-1B and TNF-a (P<0.001) .Conclusion: Minocycline combined HA-mediated ultrasound can accelerate tissue regrowth ,which exert significant benefits in healing the wounds.

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Wound care in the dermatology office: Where are we in 2011?

Cited by 24 publications

References 54 publications

The first nosocomial outbreak of methicillin-resistant Staphylococcus aureus in horses in Sweden

The first nosocomial outbreak of methicillin-resistant Staphylococcus aureus in horses in Sweden

Improving diagnostic accuracy of skin biopsies

In Vivo Assessments of Minocycline combined Hyaluronic Acid-mediated Ultrasound Therapy of Infected Wound in Rats

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