Wound Care: Trial &amp; Error Yields to Knowledge

Cuzzell, Janice Z.; Stotts, Nancy A.

doi:10.2307/3464098

Cited by 6 publications

(4 citation statements)

References 25 publications

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“…In 1962, Winter concluded that moisturized wounds in piglet skin epithelizes two times faster than air exposed wounds [ 44 ]. Since then, much has been learned about wound healing mechanisms and factors that affect them [ 45 , 46 , 47 , 48 ], dramatically expanding dressing practices. Over the past years, wound dressings developed from crude applications of natural products, including plant herbs, animal fat, and honey, to tissue engineered scaffolds [ 49 ], and more than 3000 products have been developed aiming to treat different wound types and targeting different points of the healing cascade [ 50 ].…”

Section: Dressing For Wound Treatmentmentioning

confidence: 99%

Nanotechnology-Based Dressings for Wound Management

et al. 2022

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Wound healing is known to be a complicated and intricate process and commonly classified as chronic or acute. Patients with chronic wounds are of public health concern, and require more attention onto skin lesions, including atopic dermatitis. Despite being a natural process, healing can be impaired by existing chronic de diseases such as diabetes, for example. Recently, wound dressings based in nanotechnology systems have emerged as a viable option to improve the healing process. Current advances in nanotechnology-based systems to release growth factors and bioactive agents represent a great opportunity to develop new therapies for wound treatments. It is essential that healthcare professionals understand the key processes involved in the healing cascade, to maximize care with these patients and minimize the undesirable outcomes of non-healing wounds. Therefore, this review aims to summarize the healing process phases and provide a general overview of dressings based in nanotechnology using biomaterials for the release of active agents in wound site.

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Section: Dressing For Wound Treatmentmentioning

confidence: 99%

Nanotechnology-Based Dressings for Wound Management

et al. 2022

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“…This review explores the recent advances in development that offers many benefits for shifting the paradigm for herbal contraceptives [12][13][14][15]. From times, immemorial, references have been made for the plants that possess antifertility properties also [16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Mimosine - A Novel Substance and Evaluate the Lipid Peroxidation

G¹,

Thangavel²

2019

Asian J Pharm Clin Res

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Objective: The mimosine is a novel substance extracted and purified from Mimosa pudica. The present study is to evaluate lipid peroxidation (LPO). Methods: The sox halation is used to differentiate extracts. Mimosine is purified by gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS). The present study was conducted to evaluate the hepatoprotective activity of ethanol extract of M. pudica against alcohol-induced albino rats. This was evident from significant of M. pudica on LPO and antioxidants liver of rats. Results: By GC–MS and LC–MS, the mimosine is purified and it shows the highest peak. The phytochemical analysis of M. pudica and the activity of the enzyme antioxidants such as superoxide dismutase is 176.83 g and peroxidase is 0.989 g, were found to be present in the plant extract of M. pudica. In rat treated with toxic dose of alcohol, a significant increase in serum and liver were observed. Simultaneous oral administration of the aqueous extract of M. pudica reduced the lactate dehydrogenase (LDH) activity to a significant extent compared to control. LDH, a cytosolic liver marker enzyme, is a regulator of many biochemical reactions in the body tissues and the fluid. Conclusion: The result obtained in our work, existence of bioactive substance proves that it is mainly used as a traditional medicine. The phytochemical analysis indicated the presence of alkaloids, steroids, terpenoids, tannin, phenolic, saponins, proteins, and amino acids. The liver showed that the induction of alcohol causes hepatic necrosis and injury, but it is cured by M. pudica.

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“…SIPNs have been used as membranes for filtration, protective clothing, and for certain medical applications. 10,11 Woo et al 12 reported a polycarbonate/epoxy SIPN blend that exhibited improved processing performance and better mechanical properties.…”

Section: Introductionmentioning

confidence: 99%

Effect of crosslinking on mechanical and viscoelastic properties of semiinterpenetrating polymer networks composed of poly(vinyl chloride) and isocyanate crosslinked networks

Wang

Toghiani

Pittman

2000

J. Appl. Polym. Sci.

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Semiinterpenetrating polymer networks (SIPNs) of PVC/isocyanate/polytriol were prepared by premixing small (150 m dia.) porous (30% voids) unplasticized PVC particles, 10% by weight of isocyanate, and a triol at different OH/NCO mol ratios. Three types of isocyanates (methylene bis-phenyl diisocyanate (MDI), oligomeric MDI isocyanates (PAPI), and toluene diisocyanate (TDI) prepolymer/polytriol) were used. Two-roll milling was followed by hot-press curing. The tensile, flexural, and impact strengths increased when small amounts of crosslinked isocyanate networks were created in PVC. The isocyanate/polyol hydroxyl stoichiometry was varied, and the effects of crosslinking on the tensile, impact, and flexural strengths of PVC/isocyanate/ triol SIPNs were examined. The strength increments were greater when the OH/NCO mole ratio went from 0 to 0.25, than when it went from 0.25 to 1.0. In many cases, increasing OH/NCO mol ratio from 0.5 to 1.0 decreased tensile, impact, and flexural strengths. Both PAPI and MDI (30% NCO content) gave bigger improvements in the these mechanical strengths than the TDI (only 9.7% NCO). These SIPN blends exhibited lower tan ␦ peak temperatures and a single distinct loss modulus, EЉ, peak values at lower temperatures than those of PVC that had been exposed to the same processing temperatures. Substantial amounts of isocyanate networks exist in SIPN phases according to DMTA studies. The OH/NCO ratio did not generally correlate with the decreases in the glass transition temperatures in these three sets of blends.

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Wound Care: Trial & Error Yields to Knowledge

Cited by 6 publications

References 25 publications

Nanotechnology-Based Dressings for Wound Management

Nanotechnology-Based Dressings for Wound Management

Mimosine - A Novel Substance and Evaluate the Lipid Peroxidation

Effect of crosslinking on mechanical and viscoelastic properties of semiinterpenetrating polymer networks composed of poly(vinyl chloride) and isocyanate crosslinked networks

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