Wound complications following vulvar excision for nonmalignant lesions

Boyles, Glenn; Weaver, Ashlee M.; Cohn, David E.; Backes, Floor J.; Bixel, Kristin; Fowler, Jeffrey M.; O’Malley, David M.; Cosgrove, Casey

doi:10.1016/j.xagr.2021.100022

Cited by 1 publication

(2 citation statements)

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“…One study 54 reported that 40% (6/15) of women diagnosed with dVIN had invasive carcinoma on surgical histology; of 10 biopsy‐diagnosed cases of dVIN without clinical suspicion of invasive carcinoma, 20% (2/10) had occult invasive disease. Elsewhere, a 17.2% risk of occult invasive disease has been reported among women in a combined group of vHSIL/dVIN 55 . We found no evidence to support the reliable clinical exclusion of invasive disease in suspected dVIN.…”

Section: Management Of Hpv‐independent Diseasecontrasting

confidence: 78%

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The diagnosis and management of vulval intraepithelial neoplasia

Henderson,

Lewis,

Williams

et al. 2023

The Obstetric & Gynaecologis

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Key content High‐risk human papilloma virus (HPV)‐associated vulval high‐grade squamous intraepithelial lesions and HPV‐independent differentiated vulval intraepithelial lesions represent distinct disease processes with different risks of progression to vulval squamous cell carcinoma. First‐line medical management is appropriate for women with biopsy‐confirmed vulval high‐grade squamous intraepithelial lesions who have been adequately counselled on the risk of occult invasive disease. Topical treatment should be undertaken in the context of a specialist clinic because it is not suitable for all patients. Surgical management is needed for differentiated vulval intraepithelial neoplasia. Learning objectives To understand the clinical, histological, and pathological classification of squamous intraepithelial lesions and diagnostic challenges. To be able to contribute to the multidisciplinary investigation and diagnosis of squamous intraepithelial lesions. To understand the basis for patient‐centred counselling on the investigation, diagnosis and treatment of suspected squamous intraepithelial lesions. Ethical issues Treatment must be tailored towards the patient's appreciation of risk and benefit, informed by the clinical and pathological features of the disease.

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Section: Management Of Hpv‐independent Diseasecontrasting

confidence: 78%

“…Elsewhere, a 17.2% risk of occult invasive disease has been reported among women in a combined group of vHSIL/dVIN. 55 We found no evidence to support the reliable clinical exclusion of invasive disease in suspected dVIN. Medical or ablative surgical modalities are not appropriate for dVIN.…”

Section: Management Of Hpv-independent Diseasecontrasting

confidence: 59%