Wound Healing Activity of Transdermal Patches of Carica Papaya, Chromolaena Odorata, and Averrhoa Bilimbi Leaves on Incision Wounds of Hyperglycemic Rat
Tahara Dilla Santi,
Tongku Nizwan Siregar,
Amalia Sutriana
et al.
Abstract:Transdermal patches have been used for drug delivery to accelerate the wound healing process with minimum negative effect. This study evaluated the wound healing potential of transdermal patches containing Carica papaya, Chromolaena odorata, and Averrhoa bilimbi leaves extract on hyperglycemic rat as a diabetic wound model. For this purpose, a total of 40 Wistar rats aged 2 - 3 months were randomly distributed into 10 groups. The first 5 groups (P1, P2, P3, P4 and P5) consisted of normal rats which received … Show more
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