Wound Healing and Antimicrobial Activity of Cinnamomum Extract

Abstract

Plant extract exhibited unique therapeutic characteristics due to their high content of chemical formulas with multiple medical effects. The plant extracts have shown a great advancement in controlling cardiovascular and metabolic disorders, as well as, it was used as antibacterial, antifungal, anti-cancer, and anti-inflammatory agents. Cinnamomum has been used a medical herbs from ancient times along with its uses as spice in food. Cinnamomum oild and extract have shown a great perspective in many areas of human health. We have aimed to prepare an ethanolic extract from dry cinnamomum powder, and investigate its influence in vitro against four types of bacteria and one fungal strain, and again in vivo as wound healing agent in rats. The results have shown that cinnamomum extract in ethanol was exhibited good effect in growth inhibition of escherichia coli, klebsiella sp, Staphylococcus epidermidis and Staphylococcus aureus, as well as Candida albicans. The greatest effect of cinnamomum extract was obtained against the Gram positive bacterial strains S. epidermidis and S. aureus. Furthermore, cinnamomum extract has shown to be a good wound healing agent, in which rats whom treated with cinnamomum extract have shown a faster healing compared to control rats starting from the day 7. These effects make cinnamomum to be very useful in the medical field generally, and in inflammation line specifically.