“…The bark of the stems and roots of the Hippocratea excelsa (HE) plant, commonly known in the central part of Mexico as "cancerina" has been used to treat various diseases (gastric ulcers, kidney diseases, skin conditions, uterine infections, as an anti-inflammatory, as a healing agent, and for the treatment of dysentery) (Alanís et al, 2005;Apaza Ticona et al, 2022;Escobedo Hinojosa et al, 2014;Mena-Rejón et al, 2007;Navarrete et al, 2002;Velázquez et al, 2006). This plant contains active compounds such as tingenone, celastrol, galactitol, pristimerin, excelsine, friedelin, canophyllol, canophyllal, canophyllic acid, triterpenes, sesquiterpene evoninoate and pyridine alkaloids (Cáceres-Castillo et al, 2008;Calzada & Mata, 1995;Furukawa et al, 2002Furukawa et al, , 2018Mata et al, 1990;Mena-Rejón et al, 2007;Navarrete et al, 2002;Perez et al, 1995;Reyes-Chilpa et al, 2003).…”